David L. McPherson, Professor Communication Disorders and Neuroscience January 1, 2017 – December 31, 2018 Executive Summary The purpose of the MEG was to mentor students into an active research environment where new neuroimaging techniques were being developed and utilized to describe the auditory system. Approximately 18 undergraduate and graduate students participated in the project. […]
Search Results for: function
Rational design of multifunctional enzyme-like catalysts for assembly-line chemical synthesis
David Michaelis – Department of Chemistry and Biochemistry Evaluation of how well the academic objectives of the proposal were met The main objectives of this proposal was to publish our preliminary findings in peptide catalysis and then submit applications for external funding. Both of these objectives were accomplished during the grant period. In the Fall […]
Determining the Role of CD5 in regulatory T Cell Function
Charles Teames and Scott Weber, Microbiology & Molecular Biology Introduction Regulatory T cells (Tregs) inhibit the immune response and play a key role in preventing autoimmunity. Unfortunately, Tregs also often prevent an effective immunological response against cancer. CD5 is a T cell surface protein known to regulate the threshold for T cell activation. CD5 is […]
Modeling Main Group Metal Alkane Functionalization Reactions in Highly Acidic Carboxylic and Sulfuric Acid Solvents
Lily H. Carlson, Prof. Daniel H. Ess, Chemistry Department Our group is interested in identifying the unknown mechanisms of main-group C-H functionalization reactions. In the long term, our goal is to use computational chemistry tools to develop general principles on mechanisms, intermediates, reactivity, and selectivity for hydrocarbon C-H functionalization reactions by p-block main-group compounds as well […]
CD5 Deficient Mice Exhibit Altered Cognitive Function in Behavioral Studies
Tyler Cox, Work done in lab of Dr. Scott Weber, Microbiology and Molecular Biology Department Introduction The immune system plays a role in protecting and maintaining the central nervous system (CNS). 1Dysfunctions within the immune system can affect the CNS and it is associated with diseases such as Multiple Sclerosis, Alzheimer’s and Parkinson’s disease. Having an […]
The effect of Nr4a3 on functional Beta Cell Mass
Jeffery S. Tessem, Nutrition, Dietetics, and Food Science Evaluation of academic objectives The academic objectives of this Mentoring Environment Grant (MEG) were to 1) train undergraduate students in the scientific process to prepare them in careers as physicians and scientists, and 2) to determine if the in vitro phenotypes observed in Nr4a3 deficient beta cell […]
Functional Optimization of Carbon Nanotubes
Taylor Davis and Sr. Brian Iverson, Mechanical Engineering Department Introduction The objective of this project was to create, characterize, and optimize carbon nanotube (CNT) films as a surface functionalization strategy through modifying the growth, infiltration, and patterning during fabrication. Carbon nanotubes have drawn attention in various disciplines in the scientific community because of their incredible […]
Predicting Bacteriophage Gene Function through Secondary Structure BLAST
Corinne Sexton and Faculty Mentor: Perry Ridge, Biology Introduction Bacteriophages are viruses that specifically target bacteria. With antibiotic resistance on the rise, some researchers are looking to bacteriophages as a viable treatment alternative. Phage therapy would be effective for a host of reasons, some of which are because phages are 1) highly specific to their […]
RAGE functions during Secondhand Smoke-Induced Bronchopulmonary dysplasia
Brent Kimber and Faculty Mentor: Dr. Paul Reynolds, Physiology and Developmental Biology Introduction Bronchopulmonary Dysplasia (BPD) is a common respiratory disease among pre-term infants or newborns exposed to harmful toxins during pregnancy or at birth. This leads to several respiratory diseases later in life such as chronic obstructive pulmonary disorder (COPD) or asthma. However, research […]
Function of Ric-8A in G protein e+- Subunit Biogenesis
PI: Barry Willardson Students Involved Grant Ludlam. The MEG award helped support Grant’s work from January 2015 through August 2016. During this time Grant has worked on three projects. He investigated the role of Ric8A in the folding of the G protein a subunit and its assembly into the G protein heterotrimeric complex. Unfortunately, his […]
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