Dr. Richard Watt, Department of Chemistry & Biochemistry Evaluation of Academic Objectives. Background: Anemia that accompanies inflammation is associated with negative outcomes for patients. Early intervention to treat anemia is an important step in improving the quality of life for anemic patients. Our lab proposed to develop simple diagnostic tests using a Lateral Flow Immunoassays […]
Rational design of multifunctional enzyme-like catalysts for assembly-line chemical synthesis
David Michaelis – Department of Chemistry and Biochemistry Evaluation of how well the academic objectives of the proposal were met The main objectives of this proposal was to publish our preliminary findings in peptide catalysis and then submit applications for external funding. Both of these objectives were accomplished during the grant period. In the Fall […]
Carbohydrate Vaccines and Mimics of Antimicrobial Peptides submitted on 11/30/15
Paul B. Savage, PI, Department of Chemistry and Biochemistry Evaluation of how well the academic objectives of the proposal were met The primary academic objective of the proposal was to provide a research experience for undergraduate students working on two projects closely associated with drug development. Funds from the grant were used exclusively to pay […]
Mentoring Undergraduates at the Intersection of Organic Synthesis and Peptide Science
PI: Steven L. Castle Introduction This report summarizes the results that were generated under the auspices of the mentoring environment in my laboratory from January 2015 to the present. A total of ten undergraduates participated in the mentoring environment during this period. Their names and accomplishments are listed below. Evaluation of Academic Objectives Our academic […]
Alzheimer’s Disease: A New Model Defining the Mechanism of Iron- Catalyzed Radical Damage to Neurons
PI: Richard Watt Co-PI: Jonathan Wisco The MEG proposal focused on understanding how elevated homocysteine levels cause the inability of cells to control iron levels as a cause for Alzheimer’s disease. Iron is associated with the amyloid plaques and tau tangles that are proposed to cause damage to neurons. Dr. Wisco and I previously submitted […]
Function of Ric-8A in G protein e+- Subunit Biogenesis
PI: Barry Willardson Students Involved Grant Ludlam. The MEG award helped support Grant’s work from January 2015 through August 2016. During this time Grant has worked on three projects. He investigated the role of Ric8A in the folding of the G protein a subunit and its assembly into the G protein heterotrimeric complex. Unfortunately, his […]
Nanomaterials Used to Destroy Water Contaminants
Roger Harrison 1. Evaluation of how well the academic objectives of the proposal were met Students working in the mentoring environment synthesized nanomaterials composed of ZnO and characterized the materials by SEM, TEM, XRD, and IR. They then used the materials as efficient photocatalysts to destroy dyes. They applied reactions and knowledge they had learned […]
Organic Synthesis as a Platform for Mentoring Undergraduates
Steven L. Castle, Department of Chemistry and Biochemistry Introduction This report summarizes the results that were generated under the auspices of the mentoring environment in my laboratory from January 2014 to the present. A total of six undergraduates participated in the mentoring environment during this period. Their names and accomplishments are listed below. Evaluation of […]
Mechanism of Assembly of the Bardet-Biedel Syndrome (BBS) Complex
Barry M Willardson, Chemistry and Biochemistry Students Involved Devon Blake. Devon was the most productive student I have had in my 18 years at BYU. The MEG award helped support his work from January 2013 through May 2014. During this time, Devon co-authored two papers on the effects of cell-type specific deletion of phosducinlike protein […]
Supramolecular Chemistry for Undergraduate Students
David V Dearden, Roger G Harrison, John D Lamb, Chemistry and Biochemistry Evaluation of how well the academic objectives of the proposal were met The goal of this proposal was to train graduate and undergraduate students through research experiences in supramolecular chemistry in a multi-group environment. Academically, our objective was to synthesize and characterize new […]