Jillian Markham and Dr. Brian Poole, Microbiology and Molecular Biology Background Epstein-‐Barr Virus (EBV) causes infectious mononucleosis upon primary infection, commonly known as “mono.” Less commonly known is that EBV doesn’t get eradicated from your body after you recover from mono. EBV quietly occupies a small portion of B cells in 90% of human adults […]
Search Results for: expression
Determining Gene Expression Levels in Healthy and Degraded Alpaca Spinal Discs
Loyd Christensen and Dr. Laura C. Bridgewater, Micro and Molecular Biology Introduction Intervertebral Disc Degeneration (IDD) is a disease estimated to affect between 60 and 90 percent of the total population at some point in life. Evidence of spinal disc degeneration has been shown in 30 percent of individuals under 40 years old, with earliest […]
Expression of HtrA1 and TgfB1 in Osteoarthritis
Karl Andersen and Dr. David Kooyman, Physiology and Developmental Biology Osteoarthritis increasingly debilitates and causes discomfiture to millions of people worldwide. Most people over 65 years of age suffer from symptoms of osteoarthritis. There has, up to this point, been effectively no clear understanding of the processes of the body that contribute genetically or mechanically […]
IRF7 expression in B cells infected with EBV
Michael Ahlborn and Dr. Brian Poole, MMBIO Dept. Introduction Systemic lupus erythematosus, commonly known simply as lupus, is an incurable autoimmune disorder that can cause inflammation and tissue damage in virtually any part of the body. Many studies have shown a correlation between lupus diagnosis and positive infection with Epstein-Barr Virus (EBV). Scientists currently estimate […]
Children’s Expressions: Using the Creative Process of Theatre to Instruct and Inspire Children in the Community
Danielle Peterson and Dr. Megan Sanborn Jones, Dept. of Theatre and Media Arts The Project Most children’s theatre involves adults putting on plays for kids. Rarely are the children given the opportunity to sit in the creative seat. With this particular project, I attempted to shift the paradigm of “children’s theatre.” Working with the local […]
Genetic Rescue of the Irk 2 Knockout Phenotype by Ectopic Expression of Irk 2 WT
Brandon Gassaway and Dr. Emily Bates, Department of Chemistry and Biochemistry Anderson-Tawil Syndrome (ATS) is characterized by morphological defects including clinodactyly (abnormal curvature of digits), syndactyly (fused digits), micrognathia (small jaw), cleft palate, and hypertelorism (wide-set eyes) as well as periodic paralysis and heart arrhythmia. Mutations in inwardly rectifying potassium (Irk) channels are found in […]
Over-expression of AGE Receptors in the Adult Mouse Lung A New Model for the Study of COPD
Megan Stogsdill and Dr. Paul Reynolds, Physiology and Developmental Biology Receptors for advanced glycation end products (RAGE) are receptors that can bind a variety of ligands and are members of the immunoglobin family of cell surface receptors. RAGE is found in many tissue types during inflammatory lesions but is found most abundantly in the lung, […]
Diagnostic and Therapeutic Potential of the Over-expression of Nucleotide Salvage Pathway Enzymes to the Plasma Membrane of Solid, Cancerous Tumors
Daniel Sharp and Dr. Kim O’Neill, MMBio Immunotherapy is a developing field in cancer treatment that relies upon the bodies natural defenses to target and eliminate cancerous cells. In order for the immune system to differentiate cancerous tissue from normal tissue there must be some mechanism for targeting only cancerous cells. Without a targeting mechanism, […]
FLOWERING LOCUS T Homologs Flower Induction Gene Expression
Robert Nielsen and Dr. Craig Colemon, Plant & Wildlife Sciences FLOWERING LOCUST like (FTL) genes are crucial regulators of flowering in angiosperms. Recent discoveries have shown that flowering in young seedlings of C. rubrum, a model plant for the study of photoperiodic flower induction, and a close relative of C. quinoa, is highly inducible by […]
RAGE Expression in Inflammatory Lung Diseases Triggered by Air Pollutants
Tyler Earley and Dr. Paul Reynolds, Physiology and Developmental Biology I was given a research grant of $1,500. My project was centered around discovery of cellsignaling pathways linked to inflammation specific to the lung. We studied a receptor that may be shown to integrally participate in inflammation in such diseases as COPD and Asthma. My […]
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