Kyle Kener and Jeffery Tessem, Nutrition, Dietetics, and Food Science Diabetes, a disease characterized by the inability of the body to maintain a normal blood glucose level, continues to affect the lives of many. In both Type I and Type II diabetes, eventual β-cell destruction results in decreased β-cell mass. Regeneration of functional β-cells and […]
Archives for February 2016
Alzheimer’s Disease and the p.V236E Variant in the ApoE Gene
Alton Chad Sorensen and John Kauwe, Physiology and Developmental Biology I was interested in trying to validate the findings of the publication by Medway et al. concerning the SNP rs199768005 using data from the Cache Country data set. Unfortunately, of the 4703 people from our data set, only 10 were carriers. Using R statistical analysis, […]
The Role of PAS Kinase and the Gut Microbiome In Metabolism and Diabetes Onset in Mice
Andrew Rees and Laura Bridgewater, Microbiology and Molecular Biology Diabetes and obesity are among the most prevalent health concerns in the modern world. However, prevention of their onset and control of their symptoms are still largely limited by our understanding of how these diseases arise. Recent research has indicated that the composition of the gut […]
Morphology of Human Myoblasts in Cultured Muscle Cells by the Novel Small Molecule SGI
Ryan Matekel and Robert Hyldahl, Exercise Science Introduction Muscle wasting is a symptom of cancer, AIDS, renal failure, heart failure, aging, prolonged bed rest, and has been seen in rodent models for burn, and kidney disease (Han, 2013). Muscle wasting negatively impacts quality of life by decreasing functional independence and increasing morbidity and mortality (Anker, […]
Examination and Classification of Secondary Metabolites from Endophytes of Cornus Sericea
Madsen Sullivan and Brad Geary, Plant and Wildlife Sciences Introduction All civilizations have used plants and their byproducts to effectively grow and cultivate crops, as well as manage and treat many ailments. Even today, approximately 25% of prescribed medications are constituted by plants. Many of the active metabolites are produced in such small quantities that […]
Impact of Pregnancy Factors on the Health of Infants in Cambodia
Grace Mitton and Randy Page, Health Science Introduction The Liahona Children’s Foundation reaches out to over 800 children in seven different areas of Cambodia, from Battambang to Kampong Cham to Sen Sok. With such a widespread reach and breadth of effect it is imperative that these children are helped with the most effective efforts. During […]
Anatomical variation of the ulnar collateral ligament and implications for joing stability and surgical rehabilitation
Jakob Gamboa and Dr. Jonathan Wisco, Physiology and Developmental Biology In 1974, the first ulnar collateral ligament reconstructive surgery was performed on Los Angeles Dodgers’ pitcher, Tommy John. The damaged ligament of the medial elbow was repaired with tendons from the pitcher’s body. Since then, the surgery has been colloquially termed “Tommy John’s Surgery”, and […]
Human Fibroblast Cell Adhesion to Extracellular Matrix
Brady Vance and Alonzo Cook, Chemical Engineering Heart disease, according to the Centers for Disease Control and Prevention, is the number one cause of death in the United States, killing more than 600,000 people each year1. Due to the high incidence of heart disease and the low availability of transplantable hearts, new technologies have been […]
3D Printed Alginate Scaffolds in Regenerative Medicine Techniques
Tyler Hendricks and Dr. Alonzo Cook, Chemical Engineering Introduction Mostly an exploratory project, the goal of this study was to determine the best combination of preparation temperature and concentration of alginate gel to be used with 3D printing technologies in tissue engineering and future regenerative medicine techniques. Recognizing the role that 3D printing technologies could […]
Evidence for Regulatory T Cell in Skeletal Muscle Repair
Amanda Gier and Robert Hyldahl, Exercise Science Testing multiple immunohistochemistry protocols, I was unsuccessful at identifying Tregulatory cells in human skeletal muscle samples. A total of 5 months was dedicated to this original project before I was reassigned to look into the presence of CD8+ cells in skeletal muscle. The new project proved to be […]
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