Jeffrey C. Markham and Professor David D. Busath, Zoology The oligopeptide gramicidin is one of the simplest proteins which can form channels in cell membranes to conduct ions into or out of a cell. The peptide is produced by the bacteria Bacillus brevis. It can also be synthesized by scientists for research purposes. By producing slightly modified […]
Analysis of a Constitutively Active PhoB Mutant Protein
Chad C. Lowe and Dr. William R. McCleary, Microbiology Within the cellular environment, the processing of essential nutrients required for cellular growth and metabolism are tightly regulated. When these essential nutrients become limited in the cells surroundings, cellular stress responses are induced. This enables the cell to maintain life in less than ideal environmental conditions. […]
Phylogenetic Utility of the Astacin Gene in Crayfish
Crystal Komm and Dr. Keith Crandall, Zoology Phylogenetic analyses are used to examine evolutionary relationships among crayfish species at different taxonomic levels. Nuclear genes provide genetic information from independent loci which, when analyzed, can be compared to mitochondrial DNA sequences. Astacin is a nuclear gene encoding a digestive protein in crayfish. This was the focus […]
Hearing Native Voices: A Field-Study of Women’s Reproductive Health in the Village of Matemwe, Island of Unguja, Zanzibar East Africa
Jeremy J. Keele and Dr. Samuel Rushforth, Botany and Range Sciences Zanzibar is a tiny archipelago nation associated with the East African country of Tanzania. Thanks in part to an ORCA grant, I spent the summer of 2000 living with the villagers of Matemwe, on the archipelago’s principal island, Unguja. While in Matemwe, I studied […]
The Molecular Basis for Prostate Cancer Risk Reduction by Selenium
Josie Johnson and Dr. Merril J. Christensen, Food Science and Nutrition Prostate cancer is the most common form of cancer and the leading cause of cancer death in American men.1 Results from a cancer prevention trial performed by Clark et.al.2 show that selenium (Se) supplementation in male subjects reduced cancer incidence by 75%. The molecular […]
Non-equilibrium Molecular Dynamics Study of an Ion Channel with Aqueous NaCl: A Slab Geometry Approach
Nathan B. Holladay and Professor David D. Busath, Zoology An ion channel is a tunnel that allows ions to cross a barrier. Ion channels are common components of cellular membranes, helping to regulate ionic concentrations in different areas inside or outside cells. Electrical and/or concentration differences between one side of a membrane and the other often drive […]
Cell Transfection of Rat Chondrosarcoma Cells Assaying Col11a2 Gene Enhancer Element Activity Using Luciferase and â-galactosidase
Ann Hillam and Dr. Laura C. Bridgewater, Zoology The Col11a2 gene encodes the production of type XI collagen which is fundamental for normal skeletal development. As with many genes, comparatively little is known of the transcriptional activation and enhancement mechanisms of the Col11a2 gene. Such knowledge will help advance gene therapy techniques to minimize and […]
Survey of Mycorrhizal Colonization in Native, Open-Pollinated and Introduced, Hybrid Maize in Villages of Chiquimula, Guatemala
Jessica Hess and Dr. Von D. Jolley, Agronomy and Horticulture Mycorrhizae is a symbiotic association between certain species of soil fungi and the root systems of many land plants. Most economically important crops form this association. By colonizing plant roots, mycorrhizal fungi receive a carbon supply from photosynthesis in plant tissues. The plant, by reason […]
Phylogeny of the Polyneopterous Insect Orders
Matt Gruwell and Dr. Michael Whiting, Zoology Despite recent morphological and molecular investigations, phylogenetic relationships among the Polyneoptera remain nebulous. If this group is monophyletic, then it represents one of the largest and morphologically most diverse of all insect radiations. The Polyneoptera includes the orders Orthoptera, Phasmida, Plecoptera, Embioptera, Dermaptera, Grylloblattaria, Isoptera, Blattaria, and Mantodea, […]
Preferred Channels of Communication for Emergency Preparation
Rainie Graham and Dr. Michael D. Barnes, Health Science This report is written as a summary of the research that was conducted throughout the winter and spring of 2000 in support of the funded research proposal titled “Channels of Communication for Emergency Preparation”. This research was intended to establish the preferred communication channels for receiving […]
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