Nate Batey, Zach Frederich, Morgan Fronk, Nate Jenkins and Jonathon Hill, Physiology and Developmental Biology Introduction Congenital Heart Disease (CHD) is the most common type of birth defect in the United States, causing more first-year infant deaths than any other birth defect (1). While the causes of CHD are varied, genetic defects are known to […]
Archives for June 2018
Identifying Novel Regulators of Cellular Respiration
Sam Nicholes and Faculty Mentor: Julianne Grose, Microbiology and Molecular Biology The impetus behind my project was to contribute in a small but meaningful way to the growing body of research for cures and treatments for cancer. Cancer is fundamentally unwanted cell growth and proliferation. Metabolic processes that take place on the cellular level are […]
Dysregulation of Tenascin C and Hyaluronic Acid in Aged Skeletal Muscle
Alex Holland and Faculty Mentor: Alan Parcel, Exercise Science Introduction: Satellite cells are the progenitor stem cells of skeletal muscle (SM) that reside between the sarcolemma and basal lamina. This space is referred to as the satellite cell niche. Following injury, quiescent satellite cells are activated, proliferate then migrate and fuse to the injured region […]
“Seeing” Beyond the Knees: Inflammation in the Eye as a Result of Mechanical Stress
Michael Goodman and Faculty Mentor: David Kooyman, Physiology and Developmental biology A correlation between Osteoarthritis (OA), affecting over 27 million people in the US [1], and metabolic syndrome (MS), affecting over 340 million people worldwide [2], becomes strikingly important as the search for an effective treatment for OA continues. Increasing evidence has shown that OA […]
Incorporating Ground Juniper Wood into Sagebrush Seed Agglomerates as a Fungicide Alternative
Benjamin Hoose and Faculty Mentor: Matthew Madsen, Plant and Wildlife Sciences Sagebrush seed agglomerates (referred to as ‘agglomerates’ in the remainder of the report) are small balls of seed, clay, and compost that allow us to treat sagebrush seeds with germination enhancers. The goal of my project was to determine whether we could use the […]
Biochemical characterization of the oat CslF6 mixed-linkage glucan synthase
Alexander E. Chu and Faculty Mentor: Eric N. Jellen, Department of Plant and Wildlife Sciences Introduction The central dogma of molecular biology teaches that the information of life is stored in DNA, a linear chain of nucleotide molecules. The information in DNA nucleotides is then transcribed into RNA, which encodes the amino acids needed to […]
A metagenome-wide association study of gut microbiota in Drosophila cancer metastasis.
Anthony Caruso and Faculty Mentor: John Chaston, Plant and Wildlife Sciences Introduction It has been established by past scientific research that the gastrointestinal microbiome plays a defined role in many human diseases. Some of these diseases include inflammatory bowel disease, autism, hypertension, and even cancer. A common symptom seen in many of these diseases is […]
Cardiovascular Health and Cognitive Decline in Older Adults
Alexa Ehlert and Faculty Mentor: Evan Thacker, Department of Health Science Introduction. Cognitive impairment is a concerning issue among the population of older adults in the United States. This problem is compounded by the fact that science is largely uncertain of how to prevent cognitive decline; however, if we knew that particular modifiable behaviors associated […]
Predicting Bacteriophage Gene Function through Secondary Structure BLAST
Corinne Sexton and Faculty Mentor: Perry Ridge, Biology Introduction Bacteriophages are viruses that specifically target bacteria. With antibiotic resistance on the rise, some researchers are looking to bacteriophages as a viable treatment alternative. Phage therapy would be effective for a host of reasons, some of which are because phages are 1) highly specific to their […]
Induction of Differentiation of Human Induced Pluripotent Stem Cells into Glucose Responsive Beta Cells
Caden Duffy and Faculty Mentor: Alonzo Cook, Chemical Engineering Introduction: Type 1 Diabetes (T1D) is an autoimmune disease that affects 1.25 million people in the United States, according to the American Diabetes Association. Although there are many short-term methods for regulating blood sugar levels, the only permanent cure for T1D currently is a pancreatic or […]
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