Richard Turley and Drs. Richard A. Robison and Gregory F. Burton, Microbiology Due to recent findings that HIV replication can persist even with highly active anti-retroviral therapy (HAART), it has become increasingly necessary to develop new therapies that can be used as adjuncts with HAART, to combat HIV infection. One possible alternative strategy is to […]
Search Results for: regulation
Selenium Regulation of NF-κB Binding in Cancerous Human Prostate Epithelial Cells
Wayne K. Nelson and Dr. Merrill Christensen, Food Science and Nutrition According to the National Cancer Institute, prostate cancer is the most frequently diagnosed nonskin cancer in men. In 1997 alone, it is estimated that 209,900 men were diagnosed as having the disease. Prostate cancer is also the second leading cause of cancer related death […]
Has “Regulation Full Disclosure” Helped Level the Playing Field for Investors?
Chad Larson and Dr. Ted Christensen, School of Accountancy and Information Systems The Securities and Exchange Commission requires companies to file special reports, called Form 8-K reports, within five to fifteen days of important events that could affect shareholders’ investment decisions. For example, required filings include announcements of events such as mergers and acquisitions, changes […]
ANDROGEN REGULATION OF CALBINDIN-D28K IN RAT HYPOTHALAMIC TISSUE DURING PRENATAL DEVELOPMENT
Melanie A. Watson and Dr. Edwin Lephart, Zoology Calbindin-D28K is a calcium-binding protein that serves a potentially important role in both the development and function of the central nervous system (CNS). Previous studies indicate the dimorphic expressions of calbindin within the medial basal hypothalamus (N4BH), supporting its putative importance in the neurogenesis of sexually dimorphic […]
COST OF HOUSING REGULATION IN UTAH VALLEY-IMPACT FEES
Rhett M. Turner and Dr. Howard Bashford, Technology Education & Construction Management The purpose of impact fees is to help fund infrastructure needs brought on by new growth. The State of Utah has recently passed legislation which allows cities to charge impact fees for the construction of new homes. These impact fees can be substantial, […]
SNARE Regulation
Deborah Adams and Dr. Dixon Woodbury, Physiology and Developmental Biology SNARE proteins are involved in transporting molecules within our cells, but their mechanism of action is not well known (Figure 1). It is established that SNARE proteins aid in the process of vesicles docking at target membranes. When neuronal cells are excited calcium enters the […]
Intracellular Localization of a Novel BMP-2 Variant Protein Involved in Col11a2 Regulation
Carolina M. Montaño and Dr. Laura C. Bridgewater, Microbiology and Molecular Biology Cartilage is a type of connective tissue that is found in many parts of the skeleton and covers the joint surfaces of bones. It consists of an abundant extracellular matrix (ECM) that is produced and maintained by chondrocytes. This ECM includes type II, […]
CYTOKINE REGULATION OF ADRENAL SECRETION OF DEHYDROEPIANDROSTERONE (DHEA)
Edward C. Miner and Dr. Allan M. Judd, Zoology The adrenal cortex releases aldosterone, cortisol, and dehydroepiandrosterone (DHEA) into the blood stream. The regulation of aldosterone and cortisol release by the adrenal gland is well studied. In contrast, little is known about the regulation of DHEA secretion. Since low plasma levels of DHEA are associated […]
The Role of RPL41 in Genetic Regulation of Col11a2
David William Timme The purpose of my research was to investigate what role ribosomal protein L41 (RPL41) has in regulating transcriptional activities of the Collagen 11a2 (Col11a2) gene. Prior to the ORCA grant, I had researched identifying possible transcription factors which bound to the B/C enhancer region of the Col11a2 gene, possibly regulating transcription. This […]
Up-Regulation of DDR2 and MMP13 as a Mechanism of Osteoarthritis
Allyson and Kenneth Merrell with Dr. Robert E. Seegmiller, Physiology and Developmental Biology Background Arthritis is a painful, debilitating disease that affects sixty-six million Americans (The Arthritis Foundation 2005). Osteoarthritis (OA) results in joint degeneration caused by cartilage erosion and synovial inflammation. While the causes of OA remain unclear, current evidence suggests that both mechanical […]
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