Mark Roth and Dr. Jonathan Alder, Department of Physiology and Developmental Biology Conditional cell lines are widely used throughout biochemical research. The basic concept is that you can delete a gene you are studying upon the addition of a drug, to cells in culture, and then use the knockout cells to study the genes effects. […]
Search Results for: method
Novel Methods of Creating Mesoporous Silica Films in Conjunction with Photoresist SU-8 for use in Thin Layer Chromatography Plates
George Major and Faculty Mentor: Dr. Matthew Linford, Department of Chemistry and Biochemistry Thin Layer Chromatography (TLC) is widely used for performing chemical separations and has been a staple in separation techniques. However, the functionality and effectivity of TLC plates has not changed over the past several decades. Standard TLC plates have a slow developing […]
Decreasing Nutrient Deficiencies in Malawi Through Nixtamalization: A Sustainable Maize Fortification Method
Brooke Carroll and Faculty Mentor: Frost Steele, NDFS The purpose of this study was to address several nutritional deficiencies in a typical Malawian diet through an ancient Mesoamerican process known as nixtamalization. Calcium and niacin, both crucial micronutrients, are both increased through this maize treatment process. It requires an alkaline solution, which we created from […]
Are remote cameras and mark-recapture estimators a viable method to monitor mule deer populations?
Fullmer, Jacob Are remote cameras and mark-recapture estimators a viable method to monitor mule deer populations? Faculty Mentor: Dr. Randy Larsen, Department of Plant and Wildlife Sciences Introduction Current methods for estimating mule deer populations are costly and difficult to complete with accuracy. Biologists traditionally use ground or aerial surveys, model-based simulations, or a combination […]
Reverse-Engineering Gene Networks that can Remember Using the Manifold Boundary Approximation Method
Andrew White and Mark Transtrum, Department of Physics and Astronomy Introduction Observable biological behaviors result from the interactions of microscopic elements, which form complex systems that we can model mathematically. Ideally, mechanistic models should predict a biological system’s behavior without misrepresenting the system’s biochemistry. The method of model reduction known as the Manifold Boundary Approximation […]
Reflections in Detroit: The Personal Essay as Epistemological Method
Greg Wurm and Joey Franklin, English Department Introduction The purpose of my project was to explore and demonstrate how the personal essay could be used as more than just a literary form of the humanities, but as an epistemological method in the social sciences. I built off the work of Dr. Andrew Abbott, of the University […]
Landmark vs. Manual Tracing: A Novel Method For Hippocampal Segmentation
Bryce Owen and Faculty Mentor: Brock Kirwan, Psychology Introduction Calculating hippocampal volume from MR images is an essential task in many studies of neurocognition in healthy and diseased populations. The “gold standard” method involves hand tracing, which is accurate but laborious, requiring expertly trained researchers and significant amounts of time. As such, segmenting large datasets […]
A Method of Introducing Site Specific Mutations into the phoR Gene of the E. coli Chromosome
Cameron Woodward and William McCleary, Department of Microbiology and Molecular Biology Introduction Phosphate intake by Escherichia coli serves as a good model system to study phosphate intake by other bacteria. The pho phosphate uptake system used by E. coli is well conserved in pathogens like Vibrio cholerae (1). To better understand this important mode of […]
Alternative Methods for Assessing the Benefit of Geogrid Reinforcement on Base Materials
Jaren Knighton and Dr. W. Spencer Guthrie, Civil and Environmental Engineering Introduction The pavement engineering industry needs a quick, inexpensive laboratory testing method for evaluating the structural benefit that can be expected in the field when geogrid is incorporated in a pavement. Geogrid is typically made of rigid polypropylene with ribs that form openings, called […]
When Science Meets Art: Understanding the Results and . Methods of the American Sagger Process
Jason Palmer and Professor Brian Christensen, Department of Visual Arts Overview The aims and purposes of this ORCA funded research project were two fold; first the funds would be used to renovate a heavily used kiln in the ceramics department to allow for greater atmospheric control, operator’s ease of use, and general safety. Second we […]
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