Shelby L Ferrin and Dr. Gary M Burlingame, Psychology Group psychotherapy is a growing field of both psychological research and clinical application. Credit for this growth has been ascribed to a variety of factors, among them the efficiency of seeing multiple clients at one time. Previous research has demonstrated that group therapy is as efficacious […]
Search Results for: mechanism
New Constant-force Mechanism Configurations
Bart D. Frischknecht and Dr. Larry L. Howell, Mechanical Engineering In machine design it is often desirable to correlate output force with displacement. Incorporating a translational spring into the design creates a linear relationship between force and displacement. In contrast, if a constant output force is desired independent of displacement, solutions include pneumatic or hydraulic […]
Investigation into the Mechanisms Associated with Angiogenesis and Metastasis
Rachelle R. Olsen and Dr. Kim L. O’Neill, Microbiology and Molecular Biology Angiogenesis, the development and differentiation of new blood vessels from pre-existing vasculature, is tightly controlled during physiological processes including wound healing, growth, and development. Angiogenesis is also associated with several human malignancies including arthritis, psoriasis, and cancer. Angiogenesis, which provides a source of […]
Selenium Moderation of Estrogen Receptor-Beta (ER-b) Activation: A Mechanism for Prostate Cancer Chemoprevention
Josie Johnson and Dr. Merrill J. Christensen, Nutrition, Dietetics, and Food Science Introduction Prostate cancer is the second leading cause of cancer death in men (1). Results from a prospective cancer prevention trial showed that Se supplementation reduced prostate cancer incidence by 63% (2). One molecular mechanism by which Se may protect against prostate cancer […]
A2E-DNA Interaction: A Possible Mechanism for DNA Damage
Sierra Evelyn Dabell and Dr. Heidi R. Vollmer-Snarr, Chemistry and Biochemistry Introduction A2E, a common fluorophore found in the retinal pigment epithelial cells of the eye has been shown to have phototoxic properties. For this reason A2E has been implicated in the progressive etiology of Age-related Macular Degeneration (AMD). If the mechanism of cell death […]
An Experimental Study of the Mechanisms of Fine Particle Deposition in Kraft Recovery Boilers
Larry Baxter, Greg Hatch ABSTRACT Experiments on the deposition of fume (submicron) and particles produced during black liquor combustion indicate that deposit mass accumulation increases linearly with time and is independent of temperature gradient – results that are inconsistent with the classical explanation of thermophoresis as a driving force. Temperature-controlled, cylindrical probes in cross flow […]
Up-Regulation of DDR2 and MMP13 as a Mechanism of Osteoarthritis
Allyson and Kenneth Merrell with Dr. Robert E. Seegmiller, Physiology and Developmental Biology Background Arthritis is a painful, debilitating disease that affects sixty-six million Americans (The Arthritis Foundation 2005). Osteoarthritis (OA) results in joint degeneration caused by cartilage erosion and synovial inflammation. While the causes of OA remain unclear, current evidence suggests that both mechanical […]
EVALUATION OF A COMPLIANT OUT-OF-PLANE MICRO-MECHANICAL MECHANISM
Jeff Young and Dr. Larry Howell, Mechanical Engineering Much research is being done around the world in the field of micro-electro-mechanical systems (MEMS). MEMS are devices such as linkages, actuators, gears and motors built on a scale of microns. MEMS have many potential applications in medical science, electronics and other areas where smaller, more intricate, […]
Mechanism of Translation Termination
Michael Pfeiffer and Dr. Allen Buskirk, Chemistry and Biochemistry Background Each cell within our body contains thousands of different kinds of proteins, each with a different function. Proteins provide cellular structure and perform catalysis of chemical reactions in the cell. Every protein is synthesized as ribosomes link together amino acids in the order encoded by […]
Identifying the Mechanisms of Estrogen Receptors in Human Breast Cancer Cells through Study of Direct Target Gene Expression
Megan Lundell and Dr. Chin-Yo Lin, Microbiology and Molecular Biology Estrogens, including estrodial (E2), are known to play a significant role in a number of developmental and physiological processes including the genesis and progression of breast cancer. The action of estrogens is mediated by estrogen receptors (ERs), which function as ligand-dependent transcription factors. Upon ligand […]
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