Dustin Danowski and Professor David Busath, Department of Physiology and Developmental Biology Botulinum Neurotoxin (BoNT) is currently being widely researched a a possible treatment for many medical conditions, as well as for cosmetic purposes. However, the mechanism describing how this family of toxins interact with their receptors to cause endocytosis is not well understood. We have developed […]
Search Results for: molecular
Molecular Identification of Nematode Gut Contents
Quinn Martin and Dr. Byron Adams, Biology Abstract Species-specific food web relationships involving free-living microbivorous nematodes are not well established, yet critical to our understanding of their involvement in nutrient cycling and ecosystem function. Antarctic soil ecosystems are the simplest on earth and serve as a model system for exploring the role of biodiversity in […]
Molecular Mapping of the Tomato Spotted Wilt Virus Resistance Gene Sw-7 in Tomato
Keri G. Dockter, Derek S. O’Neil, David L. Price, John Scott, and Mikel R. Stevens, Plant and Wildlife Sciences Tomato spotted wilt virus (TSWV), vectored by several thrips species, is the causal agent of devastating tomato crop losses in many areas of the world. Recently, field tests have demonstrated that there are TSWV isolates that […]
Antarctic Plectus Biodiversity: A Molecular and Morphological Analysis
Adam Clayton and Dr. Byron Adams, Department of Biology Nematodes are known to play important roles in ecosystem functioning, however their specific roles may vary across different taxonomic levels. Correct identification of nematode species is necessary when analyzing their diversity in order to effectively assign their functional role(s). Several different kinds of nematodes are known […]
RESEARCHING MOLECULAR MECHANICS
Kent Bower, Chemistry The use of Molecular Mechanics has taken a strong foothold in the world of computational chemistry today. Molecular Mechanics methods offer quick solutions to complex molecular conformation calculations that could take up to days or even months to perform on supercomputers using more exact methods, such as ab initio calculations. For this […]
Walking stick (Insect: Phasmida) Phylogeny and the Evolution of Insect Flight Based on Molecular Data
Taylor J. Maxwell and Dr. Michael F. Whiting, Zoology The evolution and development of wings and flight has fascinated scientists for decades. From our research we happened upon an exciting discovery concerning flight in the phylogeny of walking sticks. A basic phylogeny was to be reconstructed from molecular data with the purpose of understanding the […]
The Molecular Basis for Prostate Cancer Risk Reduction by Selenium
Josie Johnson and Dr. Merril J. Christensen, Food Science and Nutrition Prostate cancer is the most common form of cancer and the leading cause of cancer death in American men.1 Results from a cancer prevention trial performed by Clark et.al.2 show that selenium (Se) supplementation in male subjects reduced cancer incidence by 75%. The molecular […]
Non-equilibrium Molecular Dynamics Study of an Ion Channel with Aqueous NaCl: A Slab Geometry Approach
Nathan B. Holladay and Professor David D. Busath, Zoology An ion channel is a tunnel that allows ions to cross a barrier. Ion channels are common components of cellular membranes, helping to regulate ionic concentrations in different areas inside or outside cells. Electrical and/or concentration differences between one side of a membrane and the other often drive […]
Understanding the Molecular Targets of Antimicrobial Chemokines
Brittany Kartchner and Dr. Eric Wilson, Department of Microbiology and Molecular Biology For this project, I hypothesized that the amino acid composition of the C terminus of chemokine proteins allows some chemokines to bind to different sites on the bacterial cell wall and that the chemokines with a strong positive charge (CCL25 and CCL28) will […]
Molecular Mechanisms of Lupus Risk Conferred by Allele in the Gene for Interferon Response Factor 5
Dr. Brian Poole, Department of Microbiology & Molecular Biology Evaluation of how well the academic objectives of the proposal were met The academic objectives of this proposal were met. Using the funding provided by the MEG, we generated data that was used to publish four peer-reviewed journal articles and one peer-reviewed book chapter. These are: […]
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