Miles Murri and Dr. Brian D. Poole, Microbiology and Molecular Biology Main Text For the last year I have been working on a project that would test the efficacy of a potential drug on a common human virus called Epstein-Barr Virus (EBV). Though the virus often resides in a latent or dormant state, it is […]
Search Results for: cancer
Potential Synergism between Antioxidants found in Blueberries (Vaccinium Cyanococcus)
Richard Low and Dr. Tory Parker, Department of Nutrition, Dietetics, and Food Science Main Text According to a review by Battino et al. (2009), blueberry consumption can regulate blood pressure, inhibit cancer growth, and improve cardiovascular health by preventing plaque buildup in the arteries. Naturally occurring antioxidants found in fruits and vegetables that are thought […]
Lifetime Dietary Exposure to Soy Isoflavones Is Beneficial to Prostate and Testicular Health in 100-Day Old Male Long-Evans Rats
Benjamin Hogan with Dr. Edwin Lephart, Department of Physiology & Developmental Biology Phytoestrogens are plant-derived compounds that are structurally and functionally similar to estradiol. Isoflavones are a major type of phytoestrogen that can be found in foods such as soy beans, tofu, and soy milk. They have become popular due to the health benefits they […]
The Role of Nectin In Zyxin Localization
Jace Bullard and Dr. Marc Hansen, Department of Physiology & Developmental Biology Abstract A major difficulty of treating cancer rises from its ability to metastasize. During metastasis, strong adhesions between cells break, allowing individual cells to separate and migrate to different locations in the body. Strong cell-cell junctions are formed by protein interactions between actin […]
Selenium’s Effect on Insulin Resistance
Scott Brunson and Professor Chad Hancock, Department of Nutrition, Dietetics, and Food Science Background Due to dramatic increases in type II diabetes, studies on insulin resistance are especially applicable to this current health issue. Previous epidemiological studies examining selenium’s effect on prostate cancer observed a possible correlation between increased risk for type II diabetes mellitus and […]
Biophysical Cell Membrane Changes During Chemotherapeutic Drug-Induced Apoptosis
Amanda Berbert and Dr. John Bell, Department of Physiology and Developmental Biology Overview Our project provided us the opportunity to gain insight into how chemotherapy drugs affect the cell membrane and how secretory phospholipase A2 (sPLA2) can work in tandem with these drugs to accelerate the cell death process. The enzyme sPLA2 produces a pro-inflammatory […]
Transmission Electron Microscope Imaging of Lipid-body COX Localization
Andrew Broadbent and Dr. Daniel Simmons, Department of Chemistry and Biochemistry The laboratory of Dr. Daniel L. Simmons, my mentor, studies the cyclooxygenase (COX) enzyme. Dr. Simmons is one of the world’s foremost authorities on COX, he having discovered one of its two known types, COX-2. The COX enzyme, which exists in many organisms, including humans, is responsible […]
Development of Low-Cost Point-of-Care Channel Flow Constriction Immunoassays for the Developing World
Neil Anderson and Dr. Adam Woolley, Department of Chemistry and Biochemistry Biomarkers have a tremendous capacity for use in screening for various diseases, including cancer, diabetes, and bacterial infections. Existing immunoassay methods can detect a broad spectrum of biomarkers. However, they are costly to perform for small numbers of samples and require bulky, expensive instrumentation, making these methods unfit […]
Englerin-A
Curtis Allred and Dr. Merritt Andrus, Department of Chemistry and Biochemistry My project has been to synthesize smaller, simpler analogs of a molecule that is effective against renal cancer, called englerin-A. This is accomplished by computer aided modeling of simple analogs, synthesis of those models, and assays to determine activity. I am participating in this project in Dr. […]
Dynamical Structure Function Identifiability Conditions Enabling Signal Structure Reconstruction
Julius Adebayo and Dr. Sean Warnick, Department of Computer Science Networks of controlled dynamical systems exhibit a variety of interconnection patterns that can be interpreted as the structure of a system. One such interpretation of system structure is a system’s signal structure, characterized as the open-loop causal dependencies among manifest variables and represented by its dynamical structure function […]