Coray Preece and Robert Hyldahl, Exercise Sciences Fibroblasts play a key role in repairing injured tissue by secreting collagen and growth factors into the tissue. In states of disease and overuse, fibroblast activity (i.e. greater fibroblast content and collagen secreting activity) can lead to skeletal muscle fibrosis, in which myofibers are replaced by collagen, decreasing strength […]
Effects of Transcutaneous Electrical Nerve Stimulation on Quadriceps Activation and Walking Mechanics in Patients with Anterior Knee Pain
Brian Wiseman and J. Ty Hopkins, Exercise Sciences Introduction More than ten million people in the U.S. suffer from knee pain, and one in every two people may develop chronic knee pain by age 85.3 Knee pain is also 1 of 5 leading causes of disability among adults, and alters muscle function and walking mechanics, […]
Morphology of Human Myoblasts in Cultured Muscle Cells by the Novel Small Molecule SGI
Ryan Matekel and Robert Hyldahl, Exercise Science Introduction Muscle wasting is a symptom of cancer, AIDS, renal failure, heart failure, aging, prolonged bed rest, and has been seen in rodent models for burn, and kidney disease (Han, 2013). Muscle wasting negatively impacts quality of life by decreasing functional independence and increasing morbidity and mortality (Anker, […]
Evidence for Regulatory T Cell in Skeletal Muscle Repair
Amanda Gier and Robert Hyldahl, Exercise Science Testing multiple immunohistochemistry protocols, I was unsuccessful at identifying Tregulatory cells in human skeletal muscle samples. A total of 5 months was dedicated to this original project before I was reassigned to look into the presence of CD8+ cells in skeletal muscle. The new project proved to be […]
Effect of Myostatin Pathway Inhibition on Fibroblast Activity Using a Novel Small Molecule
Seth Hampton and Dr. Robert Hyldahl, Exercise Science Introduction Fibroblasts play a key role in repairing injured tissue by secreting collagen and growth factors into the tissue. In states of disease and overuse, fibroblast activity can become overly abundant and can lead to skeletal muscle fibrosis, decreasing strength and muscle elasticity. This fibrotic condition can […]
Foot Strike Angle Changes During Shod, Minimalist, and Barefoot Running, and Correlation to Injury
Ani Henriksen and Dr. Sarah Ridge, Biomechanics Introduction Running is a popular form of exercise. With high incidence of injury, runners are always looking for the next cure to stay injury free. Many webpages offer conflicting advice about shoes and foot strike. Although recommendations vary, barefoot running and use of minimalist shoes has increased. With […]
Inhibition of the Myostatin Signaling Pathway in Cultured Muscle Cells by a Novel Small Molecule
Ryan Matekel and Robert Hyldahl, Exercise Sciences Introduction Muscle wasting is a symptom of cancer, AIDS, renal failure, heart failure, aging, prolonged bed rest, and has been seen in rodent models for burn, and kidney disease (Han, 2013). Muscle wasting negatively impacts quality of life by decreasing functional independence and increasing morbidity and mortality (Anker, […]
Dietary Fiber Intake and Body Fat Percentage in Middle-Age Women
Jared M Tucker and Dr. Larry A Tucker, Physical Education Obesity is a big problem in the United States. The National Center for Health Statistics indicates that more than one in every three American adults is either overweight or obese. Unfortunately, individuals with excess body weight, and especially excess body fat, are at high risk […]
Morphological Adaptation to Human Skeletal Muscle Following Four Weeks of Resistance Training: Influence of Gender
Kurt Niepraschk and Dr. Allen Parcell, Physical Education Human muscle has important individual characteristics and variations. We have looked at these individual characteristics and more importantly, the specific muscle fibers. These muscle fibers can be divided into two major types; slow twitch (Type I) and fast twitch (Type IIa and IIb) fibers. On average most […]
A Comparison of Surface and Deep Temperature Changes Using Ice and Chemical Cold Packs
Steven Allen Bernards and Dr. Kenneth Knight, Physical Education Cryotherapy (cold therapy) is the use of ice or cold in the immediate care of acute musculoskeletal injuries such as sprains or contusions. When ice or another temperature lowering product is applied soon after an injury, pain, swelling, and secondary hypoxic injury are minimized. Secondary hypoxic […]