Journal of Undergraduate Research

Michael Devonas Please see the online publication at the Journal of the American Chemical Society.

Michael Porter and Dr. John Prince, Department of Chemistry and Biochemistry Introduction Proteins are an integral part of the cell. They are responsible for metabolism, DNA replication, transportation, and responding to changes in environment. Because of their importance to the cell, proteins are often drug targets due to the important roles they play in carrying […]

Braden Myers and Jaron Hansen, Department of Chemistry and Biochemistry Project Purpose This project will demonstrate the technical feasibility of microbial pretreatment of lignocellulose for enhanced production of biogas when coupled with secondary anaerobic digestion as well as optimize the entire process. Project Importance Before anaerobic digestion of waste can reach its energy production potential, […]

Brooke Keeton and Dr. John Prince, Department of Chemistry and Biochemistry B-cell chronic lymphocytic leukemia (B-CLL) is the most common type of leukemia in adults.1 Over 75% of patients diagnosed with B-CLL are over the age of 50 years old, and have a median survival between 18 months and 3 years.2 B-CLL originates from a […]

Gideon N. Logan and Daniel Simmons, Department of Chemistry and Biochemistry Introduction Cyclooxygenase (COX) isoenzymes catalyze the first step of prostanoid synthesis, which plays a role in various conditions including pain, inflammation, arthritis, and cancer. Recently our laboratory has shown that mammalian cell lines transfected with the COX-1 splice variant, COX-3, express translationally recoded proteins, […]

Brent Kamba and Dr. Jennifer Nielson, Chemistry There is a great need for students to learn scientific skills in Uganda. Very few students pass the national chemistry exams (about 40%) and even fewer go on to study science fields in higher education. The teaching methods in Uganda are a little bit old fashion where students […]

John Jensen and Dr. Adam T. Woolley, Department of Chemistry and Biochemistry Introduction DNA origami is the method of folding a large single stranded DNA (ssDNA) with multiple smaller ssDNA “staple” strands into a predesigned shape, making it an attractive option in the bottom-up construction of nanoelectronic components, such as nanowires. These structures can be […]

Jessica Jenkins and James Patterson, Department of Chemistry and Biochemistry Introduction In many fields of work, such as medicine or pharmaceutical research, it is necessary to separate chemically similar compounds. Liquid chromatography, which involves a mixture of compounds (analyte) dissolved in a mobile phase flowing through a packed column (stationary phase), is the most widely […]

Andrew Dearden and Adam Woolley, Chemistry & Biochemistry With countless technologies that rely on microprocessors, there is a great need for increasingly smaller microelectronic components. Traditionally, manufacturers have employed a “top-down” approach to build microelectronics – that is, they have attempted to scale functional microcircuitry components down in size, hoping for similar performance in a […]

David Broadbent, Dr. Joshua Andersen, Department of Chemistry and Biochemistry The resistance of tumor cells to chemotherapy is a critical problem in the clinic and is a common cause of mortality in cancer. Emerging data suggests that resistance to chemotherapy is caused by a tumor-expressed protein called 14-3-3ζ, yet the mechanism to explain 14-3-3ζ-mediated chemoresistance […]