Josue David Gonzalez Murcia and John Kauwe, Biology Department Introduction Alzheimer’s disease is one of the top 10 causes of death in the world and the 6th leading cause of death in the United States, with 5.5 million people diagnosed with the disease. Alzheimer’s cannot be cured, prevented or slowed. Most research with Alzheimer’s disease […]
Search Results for: genetic
Epigenetic Cost Matrix
Spring Cullen and Mentor: Dr. Mark Clement, Computer Science: Bioinformatics Project Purpose Epigenetics is of vital importance, comparable to genetics, in predicting the outcome of illnesses. Bisulfite sequencing (BS) provides short DNA fragments that must be mapped in order to discover epigenetic markers. The purpose of this project is to find an optimal cost matrix […]
Expanding the Genetic Code Through Compatible Sets of tRNA Synthetase
Steven Stanley and Bradley C. Bundy, Department of Chemical Engineering The genetic code, once mainly restricted to the 20 canonical amino acids, has been expanded to include many unnatural amino acids (UAAs). These new amino acids grant novel chemistries to proteins, unlocking functionalities that could be used in vaccine development and medical diagnosis methods. Unfortunately, […]
Importance of Rare Genetic Variants in Alzheimer’s Disease (TTC3)
Devan Bursey and Dr. John S.K. Kauwe, Department of Biology Introduction Alzheimer’s is a neurodegenerative disease caused by the formation of amyloid plaques and neurofibrillary tangles. Most current research on Alzheimer’s disease has focused on using genome-wide association studies to identify common genetic variants however; past research has shown that rare genetic variants play an […]
Genetic Variation within Cotton Tissues
Kimberly Clemons and Dr. Joshua Udall, Plant and Wildlife Sciences Introduction The purpose of the copy number variation (CNV) project was to determine if there is a variation in the DNA content between tissue types of Gossypium hirsutum and Gossympium barbadense. Specifically if the cotton fiber cells contain CNV that contribute to the increased output […]
Rare Genetic Variant to the Protection of Alzheimer’s Disease
Josue David Gonzalez Murcia and John Kauwe, Biology Department Introduction Alzheimer’s disease is one of the top 10 causes of death in the world and the 6th leading cause of death in the United States, with 5.5 million people diagnosed with the disease. Alzheimer’s cannot be cured, prevented or slowed. Most research with Alzheimer’s disease […]
Genetic Basis for Rheumatic Heart Disease in High Risk Families in Western Samoa
Eleni Tukuafu and John S.K. Kauwe, Department of Biology Introduction Rheumatic heart disease (RHD) is the most common form of acquired cardiovascular disease among children worldwide and results in 233,000 deaths annually. Although genetic and environmental factors are known to contribute to RHD, not much is known about genes that increase susceptibility. RHD results from […]
Molecular Phylogenetics of Basal Insect Groups: A Team Mentored Experience
Michael F Whiting, Biology Funding was received from the BYU ORCA mentorship program during 2012-2013 to support undergraduates performing research in my lab on insect evolution, under the mentorship of postdoctoral researchers, graduate students, and myself. During 2013- 2014, this funding provided direct support for 6 undergraduates who are in various stages of completing research […]
Cultivating an undergraduate mentoring research environment by characterizing the population genetics, reproduction biology, and native distribution of a putative keystone species, Agave utahensis (Utah agave), in the Mojave Desert and Colorado Plateau
J. Ryan Stewart, Plant and Wildlife Sciences Evaluation of how well the academic objectives of the proposal were met Evaluation of the mentoring environment List of students who participated and what academic deliverables they have produced or it is anticipated they will produce Description of the results/findings of the project Description of how the budget […]
Association of Rare Genetic Variants to the Development and Progression of Alzheimer’s Disease
Cameron Schmutz and Dr. Keoni Kauwe, Biology Department INTRODUCTION Alzheimer’s disease (AD) is a fatal neurodegenerative disorder and is the leading cause of dementia.1,3 It is the sixth leading cause of death in the United States and is the only one that has no adequate prevention or cure. AD is characterized by a progressive loss […]
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