“Herceptin (Trastazumab) Causes Cardiotoxicity in Breast Cancer Patients with Prior Cardiac Trauma”

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Rick Whitehead and Dr. Kim L. O’Neill, Microbiology In 1998, approximately 10 million women reached the age of 50 years, at a rate of 5,000 women per day. Based on the age incidence data for breast cancer, this means that, within the next ten years, 296,000 women will be affected annually with breast cancer. Because […]

Species Boundaries in the Gymnodactylus darwinii complex (Reptilia, Squamata)

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Aaron N. Waite and Dr. Jack W. Sites Jr., Zoology Introduction The genus Gymnodactylus is a group of small lizards belonging to the family Gekkonidae, which occur in the east and central areas of Brazil. The species G. darwinii is restricted to the Atlantic Forest and ranges from the northeastern state of Bahia south 1500 […]

Down-regulation of HIV-1 Receptors and Inhibition of HIV-1 Entry by Prostratin Treatment

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Richard Turley and Drs. Richard A. Robison and Gregory F. Burton, Microbiology Due to recent findings that HIV replication can persist even with highly active anti-retroviral therapy (HAART), it has become increasingly necessary to develop new therapies that can be used as adjuncts with HAART, to combat HIV infection. One possible alternative strategy is to […]

A Molecular Approach to Answering an Anthropological Question Concerning Burial Customs in an Ancient Egypt Population

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Jamey Tolman and Dr. Scott Woodward, Microbiology Recent advances in DNA sequencing technology have allowed us to gain knowledge about the ancient populations of the world. A team of BYU students and faculty has excavated a group of bodies, dating from 200 B.C. to 400 A.D., found in the Fag El Gamous cemetery in Egypt. […]

Comparative Resistance of Human Papilloma Virus to Inactivation by Selected Chemical Disinfectants

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Elisabeth Tillman and Dr. Richard A. Robison, Microbiology Cervical cancer is the fifth most common cancer in humans as well as the second most common cause of cancer death in women [3]. In developing countries, cervical cancer is actually the most common female disease, constituting 30% of female cancers [1]. In the United States, cervical […]

Effects of Dietary Phytoestrogens on Calcium-Binding Proteins and COX- 2 in the Frontal Cortex of Adult Rats

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Lilyan Yi Tian and Dr. Edwin Lephart, Zoology Phytoestrogens are estrogen-like molecules found in many plants (that have a diphenolic, non-steroidal structure), such as, fruits, vegetables, legumes, whole-grain and especially soy products. These plant estrogen mimic the ability to selectively bind estrogen receptors and have recently received a great deal of investigative attention due to […]

Metabolic Response to Temperature for Six Populations of Winterfat (Eurotia lanata)

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Tonya Thygerson and Dr. Bruce N. Smith, Botany and Range Science Populations within a species (accessions) are adapted to the particular microclimate of their origin and may, or may not, grow as well when moved to different location. The purpose of this work is to examine how plants adapt their respiratory metabolism to match the […]

Evaluation of Multiple Genotypes of Soybean for Iron-Deficiency Chlorosis Resistance

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Jacob Thompson and Dr. Von D. Jolley, Agronomy and Horticulture The objective of this research was to determine if iron-efficiency controlled by one gene is a more predictably inherited trait than when iron-efficiency is controlled by multiple genes. In the calcareous soils of the upper Midwest soybean becomes deficient in iron. This deficiency causes a […]

Synergistic Effects of Vitamin C and Vitamin K3 in the WiDR Human Colon Adenocarcinoma Cell Line

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Jeffery Sivert Tessem and Dr. Byron K. Murray, Microbiology In recent years in both clinical and experimental research the benefits of vitamins as anti-cancer agents have been described. Derivatives of vitamin C have been shown to “diminish the tumor mass in inoperable tumor patients” as well as cause degeneration of hepatocellular carcinoma in rats due […]