Matthew R. Carpenter and Dr. Keith A. Crandall, Integrative Biology Among the most endangered animal groups of North America is the freshwater crayfish. Their survival has been hindered by rapid growth in the human population, water pollution, and habitat degradation. The American Fisheries Society has estimated that 50% of freshwater crayfishes are in need of […]
The Luteolytic Potential of Reduced Doses of Prostaglandin administered in the Ischiorectal Fossa (IRF)
Jacob Brinkerhoff and Dr. Roy Silcox, Physiology and Developmental Biology During the past few years of my education at BYU, I have had the opportunity to study and learn about the dairy industry and what types of management programs are in place to help ensure higher production and lower costs. One of the most important […]
Relative Rates of Molecular Evolution in Antarctic Nematodes
TJ Bliss and Dr. Byron J. Adams, Microbiology and Molecular Biology Molecular evolution is defined as any change in the genetic makeup of an organism. Since organisms of the same species and community tend to undergo similar molecular changes, rates of molecular evolution are often measured at the species level. It is well established that […]
The Effect of p53 and Resveratrol on Cell Growth and Repair
Meredith Bergin and Dr. Kim L. O’Neill, Microbiology Macrophage migration inhibition factor (MIF) induces many positive immune activities, but it has been implicated in causing cancer, specifically through its inhibition of p53, a tumor suppressing protein. It has been suggested that resveratrol, a grape seed extract, activates p53, thus suppressing tumors by inducing apoptosis. The […]
Comparison of Microbial Community Biodiversity between Pristine and Disturbed Sediments in Timpanogos Cave, National Monument
Andre Bennin and Dr. Keith A. Crandall, Microbiology and Molecular Biology Cave microbiology has been of great interest to microbial ecologists in recent years because it has enabled them to assess microbial diversity within an isolated system. An excellent example of subterranean microbial life is found in Lechuguilla Cave Carlsbad Caverns National Park, New Mexico,where […]
The Effects of a Restoration Project on the Feeding Habits of Local Trout Populations in the Provo River System
Lance Bastian and Dr. Dennis Shiozawa, Professor of Ichthyology, Integrative Biology In the fall of 1999, the state of Utah began to implement a plan involving several diversions of the Provo River. Over the course of the next several years, there arose a heated debate between the state, local ecologists and local fisherman with regard […]
Measurement of Proton Flux through Influenza A Viral Protein M2
J. Craig Moffat and Matthew A. D’Haenens with Professor David D. Busath and Dr. Dixon J. Woodbury Abstract: The Influenza A viral protein M2 is known to conduct protons across viral, Golgi, and cell membranes. M2 allows acidification of the interior of the virion thus facilitating viral RNA uncoating. In the active form, M2 is a homotetramer. […]
The CFTR Protein: Evolution and Disease
Adam Allred and Dr. David McClellan, Integrative Biology The principal aim of my research has been to aid in the understanding of complex molecular pathologies by identifying evolutionary patterns that maintain the structural and functional integrity of a particular protein product. A disease phenotype often results when such delicate patterns are disturbed. The Cystic Fibrosis […]
Virulence of Entomopathogenic Nematodes to the Citrus Root Weevil: A Comparison between Indigenous and Commercially produced Nematodes
Douglas Adolphson and Dr. Byron Adams, Biology and Agriculture The citrus root weevil is a major pest of citrus crops in Florida and the Caribbean. Currently, entomopathogenic nematodes are being used as an insecticide against the weevil. The nematodes carry bacteria inside of them as they enter the weevil. Once inside, they release the bacteria […]
SNARE Regulation
Deborah Adams and Dr. Dixon Woodbury, Physiology and Developmental Biology SNARE proteins are involved in transporting molecules within our cells, but their mechanism of action is not well known (Figure 1). It is established that SNARE proteins aid in the process of vesicles docking at target membranes. When neuronal cells are excited calcium enters the […]
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