Kevin Lowder and Dr. Tory Parker; Nutrition, Dietetics, Food Science This project was a very meaningful experience for me, as it allowed me to work closely with my mentor with the goal of publication in a scientific journal. I had approached Dr. Parker about working in his lab prior to applying for an ORCA grant, […]
Optimization and Standardization of the Oxygen Radical Absorbance Capacity (ORAC) Assay
Richard Low and Dr. Tory Parker, Nutrition Dietetics and Food Science Department Antioxidants, when consumed, have the ability to neutralize free radicals, suggesting their presence may protect human physiology from destructive oxidative processes1. Several assays have been developed that quantify the antioxidant capacity of compounds, and one assay that is commonly utilized by researchers and […]
PAS Kinase Interactions
Serena Loeb and Dr. Julianne Grose, Microbiology and Molecular Biology Prevalence of metabolic disease, primarily diabetes, is increasing at a steady rate. This trend has created a need for new treatment options. Researchers discovered that the protein PAS (Per-Arnt-Sim) kinase is involved in mammalian metabolic regulation; showing PAS kinase deficient mice exhibited decreased weight gain, […]
Search for Genomic Factors that Influence Cerebrospinal Fluid Levels of YKL40, a Novel Biomarker for Alzheimer’s Disease
Mo Lee and Dr. John S.K. Kauwe, Biology Department Alzheimer’s disease is the most common form of dementia in the United States. It is a complex neurodegenerative disorder featured by gradual onset and progression of memory loss combined with deficits in executive functioning, language, visuospatial abilities, personality, behavior and self-care. There are basically two types […]
Novel Nanoinjection of Yeast Artificial Chromosomes in Mouse Zygotes
Jordan Kitchen and Dr. Sandra Burnett, Micro and Molecular Biology Transgenic mice are used to create animal models and are typically generated by the addition of transgenes (4-14 Kb pairs) or artificial chromosomes (150-300 Kb) to the pronucleus of a fertilized mouse egg [1][2]. Because of the size of chromosomes, using them to produce transgenic […]
The Evolution of Color Vision in Dragonflies and Damselflies (Odonata)
Kelsy Johnson and Dr. Michael F. Whiting, Biology Department Opsins are the genes present in the eye that are responsible for color vision in all animals (Briscoe et al., 2001). Insect vision is particularly interesting because they are able to see different wavelengths of light due to the number and types of opsins present in […]
Phylogeny of Ensifera (Orthoptera) and the Evolution of Acoustic Communication
Jessica Jensen and Dr. Michael Whiting, Biology Ensifera is an insect suborder within the order Orthoptera that includes insects such as katydids and crickets. The evolutionary history of Ensifera is largely unknown, and there is no consensus on the phylogenetic relationships among families within Ensiera. A large part of this is due to inadequate character […]
Discovering Protein Interactions of hR120GCryAB
Kent Jarvis and Dr. Julianne Grose, Department of Micro and Molecular Biology Goal Achievement: The original goal of my project was to find substrates of hR120GCryAB using a yeast two-hybrid model. Over the past few months I was able to achieve this goal. I was able to find over 11 novel substrates that bind with […]
Osteoarthritis and Cartilage
David Holt and Drs. L.C. Bridgewater and R.E. Seegmiller Summary Objective: To test the hypothesis that the spondyloepiphesial dysplasia congenita (sedc) heterozygous (sedc/þ) mouse, a COL2A1 mutant, is a model for the study of osteoarthritis (OA) in the absence of dwarfism and to investigate the presence of HtrA1, Ddr2, and Mmp-13 and their possible involvement […]
Characterization of 10 polymorphic microsatellite loci in the South American lizard Liolaemus fitzingerii with cross-amplification in L. chehuachekenk
Nathan Hanna and Dr. Jack Sites, Biology Department Liolaemus is a genus of lizards that is very common in South America, particularly the southern regions. Distinguishing differences between separate species within the Liolaemus genus has been an ongoing pursuit, one in which Jack Sites and his lab have been extensively engaged. Liolaemus chehuachekenk is a […]
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