Dr. Jack Sites, Department of Biology This award provided $20,000 to support of molecular phylogenetic work on a number of projects, including those related to my long-term focus on the “deep history” relationships of squamate reptiles (lizards and snakes), and the second more recent emphasis on phylogeographic (“shallow history”) studies of frogs and lizards. This […]
Search Results for: protein
Down Syndrome Pathway Analysis
Dr. Mark Clement, Department of Computer Science Many of the most serious medical problems that plague humanity are caused by problems in the genetic regulatory network. Heart disease, cancer and many other maladies could be cured if we understood how genes interact with each other in order to produce different symptoms. Many of these problems […]
A Novel Nuclear Variant of nBMP-2: Role in Ca2+ Transport
Dr. Laura Bridgewater, Department of Microbiology & Molecular Biology The goal of this project was to elucidate the role that nBMP-2 plays in Ca2+ transport. In the previous year, we demonstrated that mice that have no nBMP-2 in the nuclei of their cells exhibit delays in the transport of Ca2+ back into the sarcoplasmic reticulum […]
Receptors for Advanced Glycation End-Products (RAGE) Mediates Particulate Matter-Induced Pulmonary Inflammation
Dr. Paul Reynolds, Department of Physiology & Developmental Biology Academic Objectives Met and Results Observed Funding available through this MEG award has provided an opportunity for me to meet many academic objectives I’ve determined to be important in the early stages of my faculty appointment at BYU. First of all, I have been able to […]
Soluble Epoxide Hydrolase is Down-Regulated in the Brains of Female HS Rats compared to NS Rats
Dr. James Porter, Department of Physiology & Developmental Biology Specific Question 1. Can the down-regulation of epoxide hydrolase expression determined by microarray analysis be confirmed using RT-PCR? We were able to use RT-PCR to confirm that mRNA expression for brain soluble epoxide hydrolase was significantly down-regulated. The magnitude of relative down-regulation was on the same […]
Interferon Alpha in Systemic Lupus Erythematosus
Dr. Brian Poole, Department of Microbiology & Molecular Biology Evaluation of how well the academic objectives of the proposal were met We presented data from this project at two meetings, 2 presentations at the American society for Microbiology Branch Meeting, Provo UT 2010 and one at the Intermountain Research Symposium, Logan Utah 2010. At the […]
The Function of Yeast PAS kinase
Dr. Julianne Grose, Department of Microbiology & Molecular Biology Evaluation of academic objectives PAS kinase is a newly discovered member of the nutrient sensing kinases that regulates glucose homeostasis in mice and yeast. The aim of our 2009 MEG “The Function of Yeast PAS kinase” was to characterize the role of a known PAS kinase […]
The Role of Nuclear Bmp2 (nBmp2) in Skeletal Muscle
Dr. Laura Bridgewater, Department of Microbiology & Molecular Biology The goal of this project was to characterize the molecular pathway by which nBmp2 disrupts Ca2+ handling in skeletal muscle of nBmp2 mutant mice. Previously, we had worked with Dr. Chad Hancock’s lab to measure muscle function in nBmp2 mutant mice, and those results showed a […]
How Does the Effect of Cholesterol Vary between the Inner and Outer Membrane?
Dr. John Bell, Department of Physiology and Developmental Biology Summary This proposal was designed to use fluorescence spectroscopy to identify in as much detail as possible physical properties of model membranes in effort to understand roles of cholesterol in biological membranes. The following questions were addressed: how does the effect of cholesterol differ between the […]
Advanced Biological and Biomedical Applications in Electrical Engineering
Drs. Neal K. Bangerter and Brian A. Mazzeo, Department of Electrical and Computer Engineering Summary The aim of the awarded MEG grant was to provide seed funding to establish a mentorship program for undergraduate students wishing to prepare for careers or graduate work in biological or biomedical applications of electrical engineering. Such a program has […]