Dr. John McBride, Department of Geology Evaluation of how well the academic objectives of the proposal were met The academic objectives of the proposal were to: travel to the Gorner Glacier system in southern Switzerland; set up a base camp on the glacier, operating out of the village of Zermatt, Switzerland; acquire 2D and 3D […]
Search Results for: mechanism
The Cognitive Neuroscience of Long-Term Memory
Dr. Brock Kirwan, Department of Psychology Memory is an essential cognitive ability. It allows us to use past events to guide future actions. Research in my laboratory focuses on determining the mechanics of how the brain remembers what it does. We are interested in determining what will be remembered and what will be forgotten. Specifically, […]
Secretory phospholipase A2
Dr. John Bell, Department of Physiology & Developmental Biology Abstract of original proposal Secretory phospholipase A2 (sPLA2) binds to and hydrolyzes cell membranes. It is important in inflammatory responses and diseases including septic shock, atherosclerosis, and cancer. Normally, cells resist the enzyme’s action, but they become susceptible early during the process of either biochemically-programmed or […]
Endocannabinoid Enzyme Expression in the Hippocampus
Dr. Jeff Edwards, Department of Physiology & Developmental Biology Evaluation of academic objectives of the proposal The objectives of this award were met, especially in regard to the mentoring focus of the award. The students have been mentored and trained in an effective manner as outlined below. Using this mentoring environment and the experiences gained […]
A Novel Nuclear Variant of nBMP-2: Role in Ca2+ Transport
Dr. Laura Bridgewater, Department of Microbiology & Molecular Biology The goal of this project was to elucidate the role that nBMP-2 plays in Ca2+ transport. In the previous year, we demonstrated that mice that have no nBMP-2 in the nuclei of their cells exhibit delays in the transport of Ca2+ back into the sarcoplasmic reticulum […]
Changes in Membrane Physical Properties during Chemotherapy
Dr. John Bell, Department of Physiology & Developmental Biology Abstract of original proposal Many chemotherapeutic agents treat cancer by inducing programmed cell death (apoptosis) in the tumor. One of the consequences of apoptosis is changes in the physical properties of the cell membrane. Some of these changes are important for other phagocytic cells to recognize […]
Receptors for Advanced Glycation End-Products (RAGE) Mediates Particulate Matter-Induced Pulmonary Inflammation
Dr. Paul Reynolds, Department of Physiology & Developmental Biology Academic Objectives Met and Results Observed Funding available through this MEG award has provided an opportunity for me to meet many academic objectives I’ve determined to be important in the early stages of my faculty appointment at BYU. First of all, I have been able to […]
Soluble Epoxide Hydrolase is Down-Regulated in the Brains of Female HS Rats compared to NS Rats
Dr. James Porter, Department of Physiology & Developmental Biology Specific Question 1. Can the down-regulation of epoxide hydrolase expression determined by microarray analysis be confirmed using RT-PCR? We were able to use RT-PCR to confirm that mRNA expression for brain soluble epoxide hydrolase was significantly down-regulated. The magnitude of relative down-regulation was on the same […]
Plant Diversity at Home and Abroad
Dr. Leigh Johnson, Department of Biology Academic Objectives This award supported a multifaceted mentoring environment for students with a focus on plant biodiversity. The objectives were to provide support for two students participating in a focused, study abroad program sponsored by an NSF Partnerships in Research and Education award for which the PI is a […]
The Function of Yeast PAS kinase
Dr. Julianne Grose, Department of Microbiology & Molecular Biology Evaluation of academic objectives PAS kinase is a newly discovered member of the nutrient sensing kinases that regulates glucose homeostasis in mice and yeast. The aim of our 2009 MEG “The Function of Yeast PAS kinase” was to characterize the role of a known PAS kinase […]