Scott Weber Combating infectious disease with enhanced T cell memory The following two aims are from my 2014-2015 MEG. We made great progress and completed most of both Aim 1 and Aim 2. Details on the progress for each aim are described below. Mentoring Environment This MEG allowed me to expand the size of my […]
Search Results for: disease
Alzheimer’s Disease: A New Model Defining the Mechanism of Iron- Catalyzed Radical Damage to Neurons
PI: Richard Watt Co-PI: Jonathan Wisco The MEG proposal focused on understanding how elevated homocysteine levels cause the inability of cells to control iron levels as a cause for Alzheimer’s disease. Iron is associated with the amyloid plaques and tau tangles that are proposed to cause damage to neurons. Dr. Wisco and I previously submitted […]
Assessing Diagnostic Capacity of Event-Related Potentials in Mild Alzheimer’s Disease
Jack Silcox and Bruce Brown, Department of Psychology Introduction Alzheimer’s disease is a progressive neurodegenerative disease that always results in death. Unfortunately, the death that eventually comes is preceded by vicious symptoms. A patient with the disease slowly begins to lose memory and other cognitive abilities, robbing a person of their mind and life. Alzheimer’s […]
pVAAST Anallysis of Alzheimer’s Disease Sequencing Project Pedigree Data
Kristen Crofts and John S. K. Kauwe Brigham Young University, Biology December 31, 2016 pVAAST Analysis of Alzheimer’s Disease Sequencing Project Pedigree Data Introduction Alzheimer’s disease is a progressive brain disorder affecting more than 10 percent of Americans over the age of 65 (1). This disease destroys memory and thinking skills and is a leading […]
Transition From Cardiovascular Disease to Cancer as the Leading Cause of Death in US States, 1999-2014
Michael C. Harding and Evan Thacker, Department of Health Sciences INTRODUCTION: In 1900 the three leading causes of death in the United States were pneumonia and influenza; tuberculosis; and gastritis, enteritis, and colitis.1 However, through a combination of improved sanitation, the discovery of antibiotics, and the advent of vaccination programs, deaths from infectious diseases subsided […]
AB Blood Type and Its Genetic Relationship to Alzheimer’s Disease
Mark Wadsworth and John S.K. Kauwe, Biology Introduction: Alzheimer’s Disease (AD) is a debilitating disease that has increased the hardship of many lives. Many people above the age of 65 have been diagnosed with this genetically complex disease, which financially and emotionally burdens those diagnosed and their families. Earlier this year a study was released […]
BYU undergraduates execute a familial study of non-demented individuals in high-risk Alzheimer’s disease pedigrees
John S.K. Kauwe Award Date: Jan 1st, 2013 Project Justification and Overview Successful enrollment in and completion of graduate programs requires a constellation of skills. Students must be prepared to plan and execute experiments, present their findings both verbally and in manuscript form and interact effectively with senior scientists in the field of their choice. […]
AB Blood Type and Its Genetic Relationship to Alzheimer’s Disease
Mark Wadsworth and John S. K. Kauwe, Biology Introduction Alzheimer’s Disease (AD) is a debilitating disease that has increased the hardship of many lives. Many people above the age of 65 have been diagnosed with this genetically complex disease, which financially and emotionally burdens those diagnosed and their families. Earlier this year a study was […]
Alzheimer’s Disease and the p.V236E Variant in the ApoE Gene
Alton Chad Sorensen and John Kauwe, Physiology and Developmental Biology I was interested in trying to validate the findings of the publication by Medway et al. concerning the SNP rs199768005 using data from the Cache Country data set. Unfortunately, of the 4703 people from our data set, only 10 were carriers. Using R statistical analysis, […]
Association of TM2D3 gene with lateonset of Alzheimer’s disease in Cache County
Eleni Tukuafu and Dr. John S. K. Kauwe, Biology Introduction It is estimated that 5.2 million Americans have Alzheimer’s disease. It is currently the 6th leading cause of death in America, killing around 500,000 seniors every year. A 68% increase of death from Alzheimer’s disease was observed from the year 2000 to 2010. These numbers […]
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