Melina C. Walden and Dr. Duke S. Rogers, Integrative Biology In the field of biology, the job of documenting, describing, and defining the species of the world is a critical, yet overwhelming task. By focusing research in a specific area of interest, however, scientists work to contribute one small piece at a time to the […]
Medical Options for Treating Parasitic Diseases in Ashanti-Mampong, Ghana, West Africa
Whitney Elizabeth Wheeler and Dr. James B. Jensen, Microbiology and Molecular Biology I conducted my research in Ashanti-Mampong, Ghana, West Africa over the course of 3 months. My project was to study the medical options available to patients that had malaria and/or worms. I conducted interviews of 40 patients that lived in different locations around […]
Development of a Novel Human Vestibular Schwannoma Xenograft Model in SCID Mice
John Welling and Dr. Kim O’Neill, Microbiology and Molecular Biology Introduction Vestibular Schwannoma (VS) is a benign, slow growing tumor that arises from the myelin sheath of the vestibular nerve (cranial nerve VIII). The myelin sheath is composed of flat, layered cells known as Schwann cells, which serve to insulate nerve fibers. It is increased […]
Stromal-cell Derived Factor-1α and Macrophages Increased Invasive Potential of Breast Cancer Cells
Devin Twitchell and Dr. Kim L. O’Neill, Molecular Biology and Microbiology Research has demonstrated that in some tumors, up to fifty percent of a breast tumor’s mass is composed of macrophages (1). It is well recognized that macrophages can inhibit tumor growth and, paradoxically, stimulate tumor growth and metastasis depending on the proteins produced (2). […]
Cruisin’ in the Bat-mobile: Coevolution of S-Symbiont Arsenophonus spp. in Batflies (Diptera: Streblidae)
Richard E. Trowbridge and Dr. Michael F Whiting, Integrated Biology Symbiotic relationships between bacteria and insect hosts are common, with more than ten percent of insect species relying upon intracellular bacteria for their development and survival (Braendle 2003). These symbionts can stem from an obligatory association [primary (P-) endosymbionts], involving a number of properties (e.g. […]
Induced Modulation of Membrane Polyunsaturated Fatty Acids Possibilities for Chemotherapeutic Intervention in Cancer
Christopher Trimble and Dr. Byron Murray, MMBio Introduction Polyunsaturated fatty acids have several integral functions in the human body. In addition to playing essential structural, metabolic, and cell-signaling roles, fatty acids may be involved in the onset of cancer. The fatty acid profile of a cell, which is defined as the relative ratios of individual […]
Improved Culture Technique for Mycobacterium ulcerans
Neal S. Thomson and Dr. Richard Robison, Department of Microbiology Mycobacterium ulcerans is a pathogenic bacterium and is the causative agent of Buruli Ulcer, a common mycobacterial disease similar to tuberculosis and leprosy. Buruli Ulcer is endemic to Western Africa and produces a deforming and sometimes lethal skin disease. One major obstacle for research is […]
Evolution of Thrips (Thysanoptera) Phylogenetic Patterns and Mitochondrial Genome Evolution
Mark Terry and Dr. Michael Whiting, Integrative Biology Thysanoptera (thrips) is an order of insects currently comprised of 7400 species, 1200 genus-groups, and nine living families with three fossil families (Mound, 2005). Two major suborders are recognized in Thysanoptera: Tubulifera (thrips with abdominal segment 10 tubular in shape) and Terebrantia (thrips with abdominal segment 10 […]
The Maya Defensive Earthworks and Agricultural Land Use of Tikal
Ryan Sweetwood and Dr. Richard Terry, Plant and Animal Science Concurrent with the settlement surveys and excavations, Soil scientist from Brigham Young University and from Guatemala examined 62 soil profiles and collected soil samples for analysis at the Brigham Young University soil and plant analysis laboratory. The samples are currently being characterized for physical and […]
Establishing Isotopic Patterns Among Rock Pools
Heather Semon and Professor Kent Hatch, Integrative Biology Introduction Isotopic analysis with natural markers has been applied to tracking the migration of birds and butterflies as well as many other species over large geographic scales.1-4 We wanted to zoom in on a much smaller scale and determine whether stable isotopes could be used to track the […]
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