Jonathan Dewey and Dr. Allen R. Buskirk, Chemistry and Biochemistry Analyzing the function of newly discovered genes and the proteins that they encode is crucial to the advancement of genetics, cell and molecular biology, and medicine. Scientists have implemented various methods to study individual proteins within a cell, including genetic and small-molecule dependent approaches. Our […]
Jurassic Dinosaurs and Insects: The Paleoecological Role of Termites as Carcass Feeders
Anne Dangerfield and Dr. Brooks Britt, Geology My original project focused on the comparison of postcranial bones of two species of Allosaurus with the goal of differentiating the species based on limb robustness. A detailed study of 78 bones showed that there were at least 13 individuals of Allosaurus in the Dry Mesa quarry that […]
Chemical Isolation from Plant Endophytes
David Dahl and Dr. Steven Wood, Department of Chemistry and Biochemistry The major research that I have worked with is on the extraction of biologically active compounds from plant endophytes native to the west desert of Utah and high altitude Paramo of Ecuador. For a year I have been working the Department of Chemistry and […]
ORCA Final Report: Fingerprinting the α and γ Phases of Alumina using Electron Energy-loss Spectroscopy
David Cullen and Dr. Richard Vanfleet Introduction The alpha, gamma, and kappa phases of aluminum oxide were analyzed using transmission electron microscopy. Micro- and nano-powders of alpha and gamma alumina were donated by Dr. Bartholomew of the BYU Chemical Engineering Department and Alpha Aesar. Kappa phase alumina nanopowders were generated by annealing from a gibbsite […]
Observed Physiological Changes in Na+,K+-ATPase in Bovine Lens Epithelial Cells Upon Ouabain Exposure
Steven Jason Crellin and Dr. Steven Graves, Department of Chemistry and Biochemistry Age-related cataractogenesis is a worldwide leading cause of blindness. The fact that the causes as well as the apparent symptoms of cataract are diverse has contributed to increased difficulty in the study of the ailment. However, a ubiquitous symptom in animal cataract is […]
Selective Disclosure of Digitally-signed XML Documents
Richard Todd Carlson and Dr. Kent Seamons, Computer Science The Internet and related technologies allow for the transmission and consumption of electronic data with ease. Such transactions often involve the exchange of sensitive information so security and privacy concerns often limit the extent to which these technologies are used. Systems that aim to protect security […]
Effects of Follicular Dentritic Cells on Recombination Rates of Human Immunodeficiency Virus Type 1
Ericf Burgon and Dr. Greg Burton, Biochemistry Recombination is a major mechanism that generates variation in populations of human immunodeficiency type 1 (HIV-1). Mutations often confer replication advantages, such as drug resistance, which can lead to increased pathogenicity. This project is the first phase of a larger projected intended to study the effects of follicular […]
The Essence of Nature
Bradley M. Bricker and Dr. Steven Wood, Chemistry and Biochemistry It is the volatile aromatic compounds found in flowers that give them their distinctive aroma. These volatile compounds in their extracted form are often referred to as “essential oils.” And for thousands of years civilizations have been extracting these essential oils from flowers. There are […]
Evaluation of Fluorescent Folate bis-Retinoid Bioconjugates as Chemotherapeutic Agents
Britta Bergstrom and Dr. Heidi Vollmer-Snarr, Chemistry and Biochemistry The purpose of my project was to evaluate how effective a certain class of organic chemical compounds, known as fluorescent folate bis-retinoid bioconjugates, is for use as chemotherapy agents. An important part of my research involved developing techniques for the growth and maintenance of healthy cancer-cell […]
A Novel Asymmetric Phase-Transfer Catalyzed Approach to the Compounds Ragaglitazar and Kuarsoin A
D. Karl Bedke Asymmetric glycolate alkylation plays a key role in the synthesis of complex biologically active compounds. Such asymmetric transformations have largely to date been accomplished by employing chiral auxiliaries which have shown remarkable success in asymmetric synthesis. However, auxiliaries must also be used in stoichiometric amounts and can become quite expensive. A catalytic […]
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