Mo Lee and Dr. John Kauwe, Department of Biology It turns out that the data for chromosome 21 didn’t come to me at all. There were some problem with the data itself according to our co-researchers. However, the data for the phenotype YKL40, which is a promising gene that might affect the pathology of Alzheimer’s Disease. Dr. […]
Phylogeny of Acridoidea (Orthoptera: Caelifera) based on Complete Mitochondrial Genome Data: Testing Partition Strategies
James Leavitt and Dr. Michael Whiting, Department of Biology Goal/Purpose of the Project The orthopteran superfamily Acridoidea (Orthoptera, Caelifera), which includes grasshoppers and their nearest relatives, is the largest of the orthopteran superfamilies and provides an excellent model for studying the evolution of mitochondrial genomes. Ultimately I was able to reconstruct a phylogeny for Caelifera […]
Assessing the Effects of the IRF5 Exon 1B on Translation
Jared Lambert and Dr. Brian Poole, Department of Microbiology and Molecular Biology With our lab’s previous finding revealing a hairpin folding structure in exon 1B (IRF5 risk allele), not found in the other first exons, this project was focused towards more fully understanding the role of IRF5 exon 1B’s hairpin structure and its effect on […]
Detection of Genetic Variants Affecting MMP Protein Expression: A genome-wide association study approach
Krista Klingler and Dr. John Kauwe, Department of Biology Alzheimer’s disease is the most common form of dementia, affecting over 35 million people worldwide. However, the pathology of the disease is not fully understood. Because of this, no cure for the disease currently exists, and once a patient has been diagnosed with Alzheimer’s disease, death […]
Understanding the Molecular Targets of Antimicrobial Chemokines
Brittany Kartchner and Dr. Eric Wilson, Department of Microbiology and Molecular Biology For this project, I hypothesized that the amino acid composition of the C terminus of chemokine proteins allows some chemokines to bind to different sites on the bacterial cell wall and that the chemokines with a strong positive charge (CCL25 and CCL28) will […]
The Efffect of Precipitation Frequency and Magnitude on Engelmann Spruce
Sarah Karlinsey and Dr. Richard Gill, Department of Biology I was able to present my findings in poster-‐form at the Ecological Society of America conference in Portland, Oregon in August. Dr. Gill and I are now in the process of writing up a paper about our work to be submitted to Tree Physiology or the […]
Development of a Dehydrated Banana Mash for the People of East Africa
Nathan Jensen and Dr. Frost Steele, Department of Nutrition, Dietetics, and Food Science This project was designed to help smallholder farmers in Eastern Africa learn how to develop a dehydrated banana mash using solar technology. This project was inspired by the need of finding a beneficial means of preserving excess banana crops in the region. […]
Accumulation of Attached Chemokines on Gram-negative Bacterial Membranes
Peter Janzen and Dr. Eric Wilson, Department of Microbiology and Molecular Biology The purpose of this project was to see if a genetic alteration to gram-negative bacteria would affect the phenotypic ability to resist the attachment of chemokines. In other words, we were trying to see if we could change the structure of a bacterium […]
Rho Kinase Pathway Inhibition and Its Effect on Epithelial-Mesenchymal Transition
Jacob Hoj and Dr. Marc Hansen, Department of Physiology and Developmental Biology The Rho Kinase Pathway is a cellular pathway that is thought to be involved in cancer metastasis, as previous research has indicated1. As indicated by the name, the Rho group of proteins are central to this pathway. Over the past year, we set […]
Student Resistance to the Inquiry Method of Instruction in the Biological Sciences
Liahona Hamblin and Dr. Jamie Jensen, Department of Biology The purpose of this study was to test student resistance to the inquiry method of instruction in tertiary introductory biology classes. Proven to be beneficial, the “inquiry” method differs from confirmatory “cookbook” laboratory experiences in that students explore phenomena and solve problems (Prince & Felder, 2007). […]
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