Charles Teames and Scott Weber, Microbiology & Molecular Biology Introduction Regulatory T cells (Tregs) inhibit the immune response and play a key role in preventing autoimmunity. Unfortunately, Tregs also often prevent an effective immunological response against cancer. CD5 is a T cell surface protein known to regulate the threshold for T cell activation. CD5 is […]
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Determining Commercial Viability of Battery via Visual Database
Sterling Baird and Dr. Robert Davis, Department of Physics and Astronomy Batteries have applications in medical, defense, communication, transportation, and a host of other technologies. In the last several years of conducting experimental energy storage research, I began noticing gaps between what literature research was reporting and the criteria industry uses to assess the commercial […]
It Runs in The Family: Determining the Most Important Characteristics in Family Health Histories
Lauren Bretzing and Faculty Mentor: Gaye Ray, Nursing Department Introduction Family health history (FHH) is a significant risk factor for many diseases and can help determine which patients need further genetic testing, lifestyle changes, and preventative screenings at earlier ages. Though recognized as an important step in controlling and preventing disease, FHH is often underutilized […]
Determining the Structure of the BBBSome
Ludlam, Grant Determining the Structure of the BBSome Faculty Mentor: Barry Willardson, Department of Chemistry/Biochemistry Introduction Bardet-Biedl Syndrome (BBS) occurs when an eight-protein complex called the BBSome is improperly assembled and can no longer function. The BBSome is responsible for trafficking membrane proteins to cilia, a projection from the cell surface packed with receptors that […]
Determining the Mechanism of Cocoa-Derived Epicatechin Enhancement of Glucose Stimulated Insulin Secretion
Benjamin Bitner, and Jeffery Tessem; Department of Nutrition, Dietetics, Food Science Introduction Due to recent increases in incidence, diabetes is now classified as a global epidemic. Diabetes results from the eventual destruction of β-cell mass, which causes decreased insulin secretion. Increasing functional β-cell mass may provide a cure for diabetes. A previous study has shown […]
Determining if c-Fos protects β-cells from Apoptosis
Kyle Kener and Jeffery Tessem, Nutrition, Dietetics, and Food Science Diabetes, a disease characterized by the inability of the body to maintain a normal blood glucose level, continues to affect the lives of many. In both Type I and Type II diabetes, eventual β-cell destruction results in decreased β-cell mass. Regeneration of functional β-cells and […]
Determining if c-Fos Regulates Glucose Stimulated Insulin
Benjamin Bitner and Jeffery Tessem; Nutrition, Dietetics, Food Science Introduction Increasing a patient’s functional β-cell mass may provide a cure for both types of diabetes. Previous studies have shown that overexpression of the homeodomain transcription factor Nkx6.1 stimulates β-cell proliferation, increases glucose stimulated insulin secretion (GSIS) and decreases apoptosis1. Functional β-cell mass is defined by […]
Determining the Size of a Light Source Using the Hanbury Brown and Twiss Effect
Adam Kingsley and Faculty Mentor: Dallin Durfee, Physics and Astronomy I. Introduction In 1956, Hanbury Brown and Twiss (HBT) published a paper1 on a method of determining the angular size of a star by comparing the intensities gathered from two detectors. They used this effect by using two photomultiplier tubes and by increasing the distance […]
Who Deserves Coverage? Determining Utahns’ Ideal Medicaid Recipient
John Griffith and Chris Karpowitz, Political Science Introduction With the passage of the Affordable Care Act, health care policy became one of the most talked about issues in the United States. As a result, many states have been grappling with the question of whether to expand Medicaid. Utah is a particularly good place to study […]
Determining the spatial relationship between iron, tau protein, and amyloid beta within the subiculum as a means to better detect Alzheimer’s disease
Brandon Herrington and Jonathan Wisco, Department of Physiology and Developmental Biology Introduction As the 6th leading cause of death in the United States1, and because of the significant deterioration it causes in the quality of life of its victims, Alzheimer’s disease is an area where research to improve its early diagnosis is paramount to establishing […]
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