Madison Lallatin, Seth Bybee, Biology Department Introduction Vanuatu is a string of active volcanic islands in Micronesia near Fiji and Australia. The islands undergo regular submersion and emersion from the ocean, and the most recent emergence was 2 million years ago (Hamilton et al. 2010). As a result, all organisms on the islands of Vanuatu have […]
Could TK1 Suppress the Immune System and Promote Tumor Development?
Joshua Keller, Roman Kovtun, Kim O’Neill, Microbiology & Molecular Biology Cancer is a widespread disease that affects millions of people worldwide and in many cases is difficult to treat. In order to find new and better treatment, it is important to understand how this disease progresses. Thymidine Kinase 1 (TK1) is a recognized biomarker that is […]
Why does handedness exist in bilaterally symmetrical organisms?
Erik S. Johnson, Jerald Johnson, Department of Biology Over the past year I accomplished almost everything I outlined in my ORCA proposal. My project focused on why organisms display handedness and how this this maintained in wild populations over time. I address this question in a tropical livebearing fish species that shows a unique form […]
Quantifying predictive value of biological data types in machine learning models of cancer outcome
Samantha Jensen, Stephen Piccolo, Biology Precision medicine is a growing movement toward utilizing molecular diagnostics to guide medical decisions. It is particularly useful when applied to cancer treatment, as knowing details about cancer stage, genetic pathology, and tumor type can inform life-saving decisions. Increasingly, physicians may use genetic, proteomic, epigenetic, and expression data to determine treatment […]
Revision of the genus Gilia of Utah
Zachariah Jaramillo, Dr. Leigh Johnson, Biology Department Introduction The genus Gilia has historically been difficult to work with because identification of the genus via a dichotomous key relies heavily on the absence of characteristics instead of the presence of unique characteristics (Johnson et al., 2004). This has caused Gilia to become a polyphyletic group that […]
Remote Sensing Approaches To Improve Water and Nitrogen Management of Kentucky Bluegrass (Poa Pratensis)
Austin Hopkins and Dr. Neil C. Hansen, Plant & Wildlife Sciences This project identifies remote sensing practices to conserve water by optimizing nitrogen (N) fertilization and irrigation strategies. Turfgrass is the most irrigated crop by area (163,800 km2 ), accounting for 1.9% of the continental U.S. This causes negative environmental impacts and puts the future […]
Association of Urban/Rural Residence with Cognitive Impairment
Matthew Harris and Evan Thacker, Public Health Introduction: 5.4 million people in the United States are classified as cognitively impaired, with 11.7% progressing to dementia annually (Plassman 2008). Alzheimer’s Disease has risen to the 6th leading cause of death in the United States, an 89% increase from the year 2000 (Alzheimer’s Association 2017). Cognitive decline, […]
Addressing The Global Eutrophication Crisis From the Ground Up: Quantifying Ecosystem Resilience to Nutrient Loading
Rebeccas Frei and Banjamin Abbott, Plant & Wildlife Sciences I conducted a project assessing the components of aquatic ecosystems to characterize their resilience to ever-increasing nutrient pollution. Since the Industrial Revolution, humans have more than doubled nitrogen inputs, and quintupled phosphorus inputs. Some of these nutrients run off into streams and rivers, resulting in an […]
Characterization of Mutant Chemokine (C-C) motif Receptor-Like 2 (CCRL2) and its Role in Inflammation and Alzheimer’s Disease
Meganne Ferrel and Dr. John S. K. Kauwe, Biology Introduction Alzheimer’s Disease (AD) is identified as a proteopathic disease that results from an extensive accumulation of amyloid plaques and neurofibrillary tangles in the brain. Several researchers have discovered that cerebrospinal fluid (CSF) contains biomarkers for AD such as Amyloid-beta and tau. Neuritic plaques in AD […]
Antenatal exposure to secondhand smoke impacts growth and cardiopulmonary energetics in 4-week-old mice
Kaleb Egbert and Paul Reynolds, Physiology & Developmental Biology Secondhand smoke (SHS) is a well-established cause of respiratory illness in infants and children who live in environments where exposure is common. Recent studies have been performed to examine the potential effects of SHS exposure on fetus’s before they are born1. The data collected suggests that […]
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