Nathan Jensen and Dr. Frost Steele, Department of Nutrition, Dietetics, and Food Science This project was designed to help smallholder farmers in Eastern Africa learn how to develop a dehydrated banana mash using solar technology. This project was inspired by the need of finding a beneficial means of preserving excess banana crops in the region. […]
Accumulation of Attached Chemokines on Gram-negative Bacterial Membranes
Peter Janzen and Dr. Eric Wilson, Department of Microbiology and Molecular Biology The purpose of this project was to see if a genetic alteration to gram-negative bacteria would affect the phenotypic ability to resist the attachment of chemokines. In other words, we were trying to see if we could change the structure of a bacterium […]
Rho Kinase Pathway Inhibition and Its Effect on Epithelial-Mesenchymal Transition
Jacob Hoj and Dr. Marc Hansen, Department of Physiology and Developmental Biology The Rho Kinase Pathway is a cellular pathway that is thought to be involved in cancer metastasis, as previous research has indicated1. As indicated by the name, the Rho group of proteins are central to this pathway. Over the past year, we set […]
Student Resistance to the Inquiry Method of Instruction in the Biological Sciences
Liahona Hamblin and Dr. Jamie Jensen, Department of Biology The purpose of this study was to test student resistance to the inquiry method of instruction in tertiary introductory biology classes. Proven to be beneficial, the “inquiry” method differs from confirmatory “cookbook” laboratory experiences in that students explore phenomena and solve problems (Prince & Felder, 2007). […]
Identifying Proteins that Interact with Human PAS kinase
Tacie Hall and Dr. Julianne Grose, Department of Microbiology and Molecular Biology When PAS kinase is knocked out in mice placed on high-fat diets, these mice show such symptoms as decreased weight gain, hypermetabolic phenotype, decreased liver triglyceride accumulation, and retained insulin sensitivity when compared with their wild type littermates.1 These symptoms are highly associated […]
Determining the Role of Kaposi’s Sarcoma-associated Herpesvirus LANA Protein in the Development of Persistent Infection
Jamie Gardiner and Dr. Brad Berges, Department of Microbiology and Molecular Biology Kaposi’s Sarcoma-associated Herpesvirus (KSHV) is a human cancer virus that causes Kaposis’ sarcoma, the most common cancer found in AIDS patients. Our lab is working to develop humanized mice as a novel animal model to study KSHV infection and related diseases, since there […]
The Neuroprotective Effects of Exercise on LTD in the Hippocampus
Adam Field and Dr. Jeff Edwards, Department of Physiology and Developmental Biology In April of 2012, IACUC committee approved the methods which we had set forth for the carrying out of the experiment. At this point we began gathering the tools and materials needed for the performing of the experiment. Mice were obtained, and the […]
Premature Osteoarthritis in the Temporomandibular Joint of Heterozygous Disporportionate Micromelia Mice
Jason Farrell and Dr. Robert Seegmiller, Department of Physiology and Developmental Biology Purpose of the Study The purpose of this study, as also summarized in the proposal for this research grant, was to analyze the temporomandibular joints (TMJs) of mice with a specific collagen defect, Disproportionate Micromelia. Examining these joints was done to provide an […]
Diversification Rates, Phylogenetic Relationships, and Character Evolution within an Ancient Group of Decapod Crustaceans (Anomura: Decapoda)
Maren Ettinger and Dr. Keith Crandall, Department of Biology The purpose of phylogenetics is to understand the evolution of a group of organisms and to resolve the relationships within groups. Once phylogenies are created, they can be used for a number of different analyses. My project focused on using a phylogeny of the infraorder Anomura […]
A Novel Role for AMP-activated Protein Kinase as a Selective Inhibitor of de novo Ceramide Biosynthesis
Kate Erickson and Dr. Benjamin Bikman, Department of Physiology and Developmental Biology The purpose of this project was to determine the cellular mechanisms that mediate AMPK-induced reductions in lipotoxicity. We predicted that AMPK activation inhibits lipotoxic ceramide biosynthesis via targeted reduction in transcription of a critical, rate-limiting enzyme involved in de novo ceramide synthesis. This […]
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