Brian Earley and Dr. Laura Bridgewater, Department of Microbiology and Molecular Biology Bmp2 is a secretory mammalian protein that plays important roles in bone development and adult pathology. Recently, a nuclear variant (nBmp2) was discovered with an unknown function for this typically secretory protein in the nucleus (Felin et al., 2010). The purpose of this […]
Novel and Integrative Approaches to Articulating the Pancrustacean Tree of Life
Alan Colver and Dr. Keith Crandall, Department of Biology The taxonomic group Pancrustacea encompasses more than half of the world species. The two main groups within Pancrustacea are the crustaceans and hexapods (insects). Understanding these two groups will aid in preservation, population control, and economic pursuits involving these groups. In our evolutionary analysis, six different […]
Validation of Possible Blood Serum Biomarkers Linked to Genetic Risk of Alzheimer’s Disease
Jesse Cobell and Dr. John Kauwe, Department of Biology Importance of the Project In 2011, the Alzheimer’s Association released in their annual facts and figures that 5.4 million people suffer from Alzheimer’s disease. Alzheimer’s is the sixth leading cause of death in the United States and is the only disease in the top ten that […]
Examining Quantitative Differences in Gait Between the PVC Prosthesis Design and the Traditional Prosthesis
David Chinn and Dr. Matt Seeley, Department of Exercise Sciences Our purpose in conducting research was to evaluate a novel, below-knee PVC prosthesis (Figure 1) relative to traditional below-knee prostheses. We aimed to collect data from the biomechanical gait analysis of amputees using the PVC prosthesis. Our desire is to help those in developing nations […]
Genetic Diversity and Conservation of Old-Growth Cross Timbers Forest
Warren Chatwin and Dr. Leigh Johnson, Department of Biology My project “Genetic Diversity and Conservation of Old-Growth Cross Timbers Forest” has been undoubtedly the best learning experience of my undergraduate career. The project did not go at all like I had planned, but it gave me a taste of realworld scientific exploration and allowed me […]
Ex Vivo Infection and Re‐isolation of Human Herpesvirus 6
Stephanie Carlson and Dr. Bradford Berges, Department of Microbiology and Molecular Biology Science rarely cooperates as anticipated, but that can often lead to unexpected insight and solution. I ran into that this semester with a certain aspect of our project. We are continuing to collect data for the American Society for Virology in late July […]
MDCK Gene Expression During EMT
Jason Burton and Professor Marc Hansen, Department of Physiology and Developmental Biology Cancer is one of the leading causes of death in the United States. This is mostly due to a lack of understanding into the function of cancer and the different mechanisms it uses to spread. The process by which cancer cells detach from the […]
Genomic and Proteomic Analysis of an Erwinia amylovora Phage
Alicia Brighton and Dr. Julianne Grose, Department of Microbiology and Molecular Biology Introduction Fireblight is a disease, caused by the bacteria Erwinia amylovora, that can infect some fruit trees, including apple and pear trees. When an infection occurs, the effects can be devastating—any infected part of the tree must be removed and destroyed, sometimes resulting […]
Cellular Mechanisms Behind Memory Formation in the Developing Brain
Spencer Bell and Dr. Jeffrey Edwards, Department of Physiology and Developmental Biology Carrying out my research project with my mentor’s assistance has provided valuable experiences and important lessons. At the present time, however, my research has not produced the results we had anticipated. We had hoped to demonstrate that a certain receptor in the brain […]
Comparisons of Amantadine Analogues against the Dominant Influenza A Virus M2 Proton Channel Mutant via Circular Dichroism Spectroscopy and Tryptophan Fluorescence Anisotropy
Trevor Anderson and Professor David Busath, Department of Physiology and Developmental Biology The influenza A virus is a severe ongoing threat to public health, accounting for over 250,000 fatalities worldwide each year. In order to actuate the virus, it is necessary for the M2 proton channel to be activated upon fusion with an endosome. This channel […]
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